3-(Trifluoromethyl)thiophene-2-carboxylic Acid CAS 767337-59-7
| CAS No. | 767337-59-7 |
| Molecular Formula | C6H3F3O2S |
| Molecular Weight | 196.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(Trifluoromethyl)thiophene-2-carboxylic Acid (CAS 767337-59-7) is a high-purity analytical reference standard with the molecular formula C6H3F3O2S and a molecular weight of 196.15 g/mol.
Based on its molecular formula C6H3F3O2S, 3-(Trifluoromethyl)thiophene-2-carboxylic Acid contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 196.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 3-(Trifluoromethyl)thiophene-2-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H3F3O2S |
| Molecular Weight | 196.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
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- 1-bromo-3,3-diethoxy-1,1-difluoropropane (CAS 1645-58-5)
- (2R,6R,8S,12S)-1-Aza-10-oxo-12-phenyltricyclo[6.4.01,8.02,6]dodecan-9-one (CAS 147406-85-7)
- 3,3-Dimethyl-2-methylenebutanoic acid (CAS 4423-82-9)
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