Aripiprazole Impurity N7 CAS 76835-17-1
| CAS No. | 76835-17-1 |
| Molecular Formula | C10H13Cl3N2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Aripiprazole Impurity N7.
CATO supplies Aripiprazole Impurity N7 (CAS 76835-17-1), a pharmacopoeial impurity reference standard (molecular formula C10H13Cl3N2, MW 267.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Aripiprazole Impurity N7 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 267.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13Cl3N2 |
| Molecular Weight | 267.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Aripiprazole Standards
- Aripiprazole HCl (CAS 1026778-41-5)
- Aripiprazole Impurity N17 (CAS 1076199-56-8)
- Aripiprazole-d8 (CAS 1089115-04-7)
- Aripiprazole-d8 (CAS 1089115-06-9)
- Aripiprazole Impurity 32 (CAS 1147995-98-9)
- Aripiprazole-d (CAS 1185116-86-2)
- Aripiprazole EP Impurity B HCL (CAS 119532-26-2)
- Aripiprazole Impurity 8 (CAS 120004-79-7)
Recommended Standards
- Atogepant Impurity 23 (CAS 1375541-24-4)
- Trimebutine Impurity 17 (CAS CATO-C4X-185817)
- Eltrombopag Impurity 125 (CAS CATO-C4X-1198125)
- 6-Fluoro-2-sulfanyl-1h-1,3-benzodiazole-4-carboxylic acid (CAS 1193387-24-4)
- 2-(Cyclobutylmethoxy)benzoic acid (CAS 1047680-59-0)
- 4-(Chloromethyl)-2-(3-methoxyphenyl)-1,3-oxazole (CAS 678165-15-6)
- 1-(3-Fluoro-2-(trifluoromethyl)phenyl)ethan-1-one (CAS 1017777-34-2)
- 2-Phenethyl-1-(trifluoromethyl)-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-1-ol (CAS 439095-60-0)
- 2,3,5-Tribromophenol (CAS 57383-81-0)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com