Ethyl 2-(4-(2-chloroacetyl)phenyl)acetate CAS 7706-78-7
| CAS No. | 7706-78-7 |
| Molecular Formula | C12H13ClO3 |
| Molecular Weight | 240.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 240.68 g/mol gives Ethyl 2-(4-(2-chloroacetyl)phenyl)acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 2-(4-(2-chloroacetyl)phenyl)acetate (CAS 7706-78-7), molecular formula C12H13ClO3 and molecular weight 240.68 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Ethyl 2-(4-(2-chloroacetyl)phenyl)acetate (C12H13ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 240.68 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13ClO3 |
| Molecular Weight | 240.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
Related Ethyl Standards
- N'-(2-chloroacetyl)-3-phenylpropanehydrazide (CAS 1225162-21-9)
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- N’-(2-chloroacetyl)-2-(2-methylphenyl)acetohydrazide (CAS 1394042-06-8)
- 1-(chloroacetyl)-4-(methylsulfonyl)piperazine (CAS 875164-36-6)
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- 6-(2-Chloroacetyl)-7-fluoro-1,2,3,4-tetrahydroquinolin-2-one (CAS 148136-15-6)
- N-(4-(2-chloroacetyl)-2,5-dimethylphenyl)acetamide (CAS 690978-46-2)
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