1-(2,2,2-Trifluoroethyl)-2,5-dihydro-1h-pyrrole-2,5-dione CAS 771-52-8

Purity 97%+In StockPharmaceutical Standards
CAS No.771-52-8
Molecular FormulaC6H4F3NO2
Molecular Weight179.10 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2,2,2-Trifluoroethyl)-2,5-dihydro-1h-pyrrole-2,5-dione CAS 771-52-8 chemical structure

Description

Structurally, 1-(2,2,2-Trifluoroethyl)-2,5-dihydro-1h-pyrrole-2,5-dione (C6H4F3NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 179.10 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

1-(2,2,2-Trifluoroethyl)-2,5-dihydro-1h-pyrrole-2,5-dione (CAS 771-52-8) is a high-purity analytical reference standard with the molecular formula C6H4F3NO2 and a molecular weight of 179.10 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(2,2,2-Trifluoroethyl)-2,5-dihydro-1h-pyrrole-2,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H4F3NO2
Molecular Weight179.10 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing
Nitrogen Atoms1

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