2-Chloro-9-(tetrahydropyran-2-yl)adenine CAS 77111-77-4

Purity 97%+In StockPharmaceutical Standards
CAS No.77111-77-4
Molecular FormulaC10H12ClN5O
Molecular Weight253.69 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-9-(tetrahydropyran-2-yl)adenine CAS 77111-77-4 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-9-(tetrahydropyran-2-yl)adenine.

2-Chloro-9-(tetrahydropyran-2-yl)adenine (CAS 77111-77-4) is a high-purity analytical reference standard with the molecular formula C10H12ClN5O and a molecular weight of 253.69 g/mol.

The molecular framework of 2-Chloro-9-(tetrahydropyran-2-yl)adenine (C10H12ClN5O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Chloro-9-(tetrahydropyran-2-yl)adenine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H12ClN5O
Molecular Weight253.69 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Halogen ContentCl-containing
Nitrogen Atoms5

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