2-chloro-5-formylthiophene-3-carboxylic acid CAS 77133-19-8
| CAS No. | 77133-19-8 |
| Molecular Formula | C6H3ClO3S |
| Molecular Weight | 190.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-chloro-5-formylthiophene-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-chloro-5-formylthiophene-3-carboxylic acid (CAS 77133-19-8), a certified reference material (molecular formula C6H3ClO3S, MW 190.60 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 2-chloro-5-formylthiophene-3-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 190.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H3ClO3S |
| Molecular Weight | 190.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related chloro Standards
- 3-Chloro-4-ethoxy-5-fluorophenol (CAS 1017778-82-3)
- 2-Chloro-4-ethyl-5-fluoro-6-methoxypyrimidine (CAS 1192479-51-8)
- (5-Chloro-2-fluoro-4-methoxyphenyl)methanol (CAS 1266177-72-3)
- 5-Chloro-3-fluoro-2-(2-hydroxyethylamino)pyridine (CAS 1280786-67-5)
- 4-Chloro-2-fluoro-3-methoxybenzyl alcohol (CAS 1323966-21-7)
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Recommended Standards
- 2-Chloro-5-fluoro-4-propoxypyrimidine (CAS 40423-59-4)
- 2-Chloro-6-fluoro-3-methoxybenzyl alcohol (CAS 886499-49-6)
- 2-Chloro-1-fluoro-3-(methoxymethoxy)benzene (CAS 860296-13-5)
- 3-Chloro-4-ethoxy-2-fluorophenol (CAS 909122-52-7)
- [2-amino-1-(pyridin-3-yl)ethyl]dimethylamine (CAS 638220-38-9)
- (R)-2-((tert-Butoxycarbonyl)amino)-2-((1R,3s,5S)-6,6-difluorobicyclo[3.1.0]hexan-3-yl)acetic acid (CAS 2735655-76-0)
- 3-(2-Methylpyridin-4-yl)propan-1-amine (CAS 1000507-72-1)
- (E)-1-(2,5-Dichloro-3-thienyl)-3-(3-nitroanilino)-2-propen-1-one (CAS 338402-04-3)
- 2,6-Dichloro-1H-indole-3-carbaldehyde (CAS 69111-62-2)
- 3-(1-piperazinyl)-1,2-Benzisothiazole HCl (CAS 144010-02-6)
- tert-Butyl 2-methyl-3-{[2-(morpholin-4-yl)ethyl]amino}propanoate (CAS 1221341-87-2)
- 2,3,4,5-Tetrachlorotoluene (CAS 1006-32-2)
- Iodomethyl isopropyl carbonate (CAS 258841-42-8)
- Eledoisin Related Peptide (CAS 2990-43-4)
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