1-(4-Chloro-3-fluorophenyl)ethane-1,2-diol CAS 1558116-77-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1558116-77-0
Molecular FormulaC8H8ClFO2
Molecular Weight190.60 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(4-Chloro-3-fluorophenyl)ethane-1,2-diol CAS 1558116-77-0 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Chloro-3-fluorophenyl)ethane-1,2-diol.

1-(4-Chloro-3-fluorophenyl)ethane-1,2-diol (CAS 1558116-77-0) is a high-purity analytical reference standard with the molecular formula C8H8ClFO2 and a molecular weight of 190.60 g/mol.

Structurally, 1-(4-Chloro-3-fluorophenyl)ethane-1,2-diol (C8H8ClFO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 190.60 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(4-Chloro-3-fluorophenyl)ethane-1,2-diol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H8ClFO2
Molecular Weight190.60 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF/Cl-containing

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