Methyl 5-Methoxy-2-thiophenecarboxylate CAS 77133-25-6
| CAS No. | 77133-25-6 |
| Molecular Formula | C7H8O3S |
| Molecular Weight | 172.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 5-Methoxy-2-thiophenecarboxylate.
Methyl 5-Methoxy-2-thiophenecarboxylate (CAS 77133-25-6), molecular formula C7H8O3S and molecular weight 172.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 5-Methoxy-2-thiophenecarboxylate (C7H8O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 5-Methoxy-2-thiophenecarboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8O3S |
| Molecular Weight | 172.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 5-Methoxy-2-(methylthio)pyrimidin-4(3H)-one (CAS 1671-08-5)
- 5-Methoxy-2-(methylsulfinyl)pyrimidine (CAS 17148-36-6)
- 2-Methoxy-2-(thiophen-2-yl)acetic acid (CAS 5371-94-8)
- 3-Methoxy-5-methyl-2-thiophenecarboxylic Acid (CAS 83261-26-1)
- 4-Methoxy-2-methylthiophene-3-carboxylic acid (CAS 87675-98-7)
- 5-Methoxy-4-methylthiophene-2-carboxylic acid (CAS 2757171-08-5)
- N-Methoxy-N-methyl thiazole-5-carboxamide (CAS 898825-89-3)
- N-Methoxy-N-methyl-thiazole-2-carboxamide (CAS 885278-18-2)
Recommended Standards
- Methyl 5-(mercaptomethyl)furan-2-carboxylate (CAS 859303-93-8)
- n-(4-(Hydroxymethyl)thiazol-2-yl)acetamide (CAS 51307-38-1)
- Methyl 5-(hydroxymethyl)thiophene-3-carboxylate (CAS 78908-94-8)
- n-(Pyridin-3-yl)methanesulfonamide (CAS 51269-92-2)
- 4-Bromo-2-methyl-5-(trifluoromethyl)aniline (CAS 1807107-41-0)
- Alphazurine A (CAS 3486-30-4)
- 3-[4-(Diphenylmethyl)-1-piperazinyl]propanamide (CAS 1211691-72-3)
- [3-(4-Ethylphenoxy)propyl]methylamine Hydrochloride (CAS 915920-72-8)
- 3-(3-Methoxybenzyl)piperidine (CAS 766487-11-0)
- Fmoc-3-bromo-L-phenylalanine (CAS 220497-48-3)
- Methyl 2-amino-3-(thiazol-4-yl)propanoate (CAS 119357-61-8)
- 3,4-dimethyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 54770-19-3)
- 2-(tert-Butyl)-5-cyclopropoxy-N-methylbenzamide (CAS 1243400-48-7)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
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