4-Fluoro-5-methoxy-2-methylaniline CAS 77153-73-2
| CAS No. | 77153-73-2 |
| Molecular Formula | C8H10FNO |
| Molecular Weight | 155.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-Fluoro-5-methoxy-2-methylaniline (CAS 77153-73-2), a certified reference material (molecular formula C8H10FNO, MW 155.17 g/mol) for analytical method development and quality control.
The molecular framework of 4-Fluoro-5-methoxy-2-methylaniline (C8H10FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-Fluoro-5-methoxy-2-methylaniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10FNO |
| Molecular Weight | 155.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- 2-(5-Fluoro-6-methylpyridin-2-yl)ethan-1-ol (CAS 1000534-34-8)
- 3-Fluoro-4-methoxy-n-methylaniline (CAS 1096989-82-0)
- 3-Fluoro-4-methoxy-2-methylaniline (CAS 1170991-81-7)
- 2-Fluoro-5-methoxy-4-methylaniline (CAS 1232505-74-6)
- 3-Fluoro-4-methoxybenzylamine (CAS 123652-95-9)
- 2-fluoro-6-(propan-2-yloxy)pyridine (CAS 1249358-97-1)
- 5-fluoro-4-methoxy-2-methylaniline (CAS 1263299-46-2)
- 5-Fluoro-2-isopropoxypyridine (CAS 1305322-99-9)
Recommended Standards
- 4-Fluoro-3-methoxy-N-methylaniline (CAS 904321-01-3)
- 5-(3-Fluorocyclobutyl)-1H-pyrazol-3-amine (CAS 2228036-45-9)
- 4-Fluoro-2-methoxy-N-methylaniline (CAS 941294-13-9)
- 5-(Aminomethyl)-2-fluoroanisole (CAS 508177-67-1)
- (R)-2-(Boc-amino)-3-[(tert-butyldimethylsilyl)oxy]-1-propanol (CAS 152491-85-5)
- (4AR,8aR)-1-Methylhexahydro-1H-pyrido-[3,4-b][1,4]oxazin-2(3H)-one hydrochloride 1147422-47-6 (CAS 1147422-47-6)
- 1-[3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl]ethan-1-ol (CAS 1341534-14-2)
- 6-Fluoro-7-methyl-8-nitroquinoline (CAS 1420791-56-5)
- N'-Cyclopentylbenzohydrazide (CAS 24214-81-1)
- 1-Bromo-3-fluoro-2-(trimethylsilyl)benzene (CAS 632324-41-5)
- 5,7-Dihydroxy-3-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one (CAS 104691-86-3)
- 3-(Pyrrolidin-2-yl)piperidine (CAS 858262-19-8)
- 2-(6-Chloro-3-(difluoromethyl)-5-methylpyridin-2-yl)acetic acid (CAS 1805078-79-8)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
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