1-Bromo-3-fluoro-2-(trimethylsilyl)benzene CAS 632324-41-5
| CAS No. | 632324-41-5 |
| Molecular Formula | C9H12BrFSi |
| Molecular Weight | 247.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Bromo-3-fluoro-2-(trimethylsilyl)benzene is closely related to fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-Bromo-3-fluoro-2-(trimethylsilyl)benzene (CAS 632324-41-5) is a high-purity analytical reference standard with the molecular formula C9H12BrFSi and a molecular weight of 247.18 g/mol.
The molecular framework of 1-Bromo-3-fluoro-2-(trimethylsilyl)benzene (C9H12BrFSi) is characterized by fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Bromo-3-fluoro-2-(trimethylsilyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12BrFSi |
| Molecular Weight | 247.18 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Br-containing |
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Recommended Standards
- (2S,3S,4S,5S)-2-(Fluoromethyl)-5-(2-nitro-1H-imidazol-1-yl)tetrahydrofuran-3,4-diol (CAS 220793-03-3)
- 2-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,2,4-triazine-3,5(2H,4H)-dione (CAS 908129-24-8)
- 2-((3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)amino)ethan-1-ol (CAS 309741-26-2)
- 10-Fluoro-4-oxo-1,4-dihydropyrimido[1,2-b]indazole-2-carboxylic acid (CAS 1630763-70-0)
- (5-Amino-4-methoxypyridin-2-yl)dimethylphosphine oxide (CAS 2903923-26-0)
- 2-(2,3-Dihydroxypropoxy)benzaldehyde (CAS 64049-48-5)
- trans-2-[4-(Trifluoromethoxy)phenyl]cyclopropanecarboxylic Acid (CAS 238431-33-9)
- (2,6-Dimethylcyclohexyl)methanamine (CAS 1261149-10-3)
- 4'-Methyl-[1,1'-biphenyl]-4-carboxamide (CAS 72366-65-5)
- (1-Methyl-4-(trifluoromethyl)-1H-pyrazol-3-yl)methanol (CAS 878204-62-7)
- Tert-butyl 4-(3-(methoxycarbonyl)-4-nitrophenyl)piperazine-1-carboxylate (CAS 1135283-55-4)
- 2-(4-Piperidylamino)ethanol Dihydrochloride (CAS 1423027-18-2)
- 1-(Bromomethyl)-2,3-difluoro-5-methoxy-4-methylbenzene (CAS 1706430-78-5)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
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