5-[2-Chloro-6-Fluoro-4-(Trifluoromethyl)Phenoxy]-N-Ethylsulfonyl-2-Nitrobenzamide CAS 77227-69-1
| CAS No. | 77227-69-1 |
| Molecular Formula | C16H11ClF4N2O6S |
| Molecular Weight | 470.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-[2-Chloro-6-Fluoro-4-(Trifluoromethyl)Phenoxy]-N-Ethylsulfonyl-2-Nitrobenzamide (CAS 77227-69-1), a certified reference material (molecular formula C16H11ClF4N2O6S, MW 470.78 g/mol) for analytical method development and quality control.
The molecular framework of 5-[2-Chloro-6-Fluoro-4-(Trifluoromethyl)Phenoxy]-N-Ethylsulfonyl-2-Nitrobenzamide (C16H11ClF4N2O6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-[2-Chloro-6-Fluoro-4-(Trifluoromethyl)Phenoxy]-N-Ethylsulfonyl-2-Nitrobenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11ClF4N2O6S |
| Molecular Weight | 470.78 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- 2-[(thiophen-3-ylmethyl)sulfanyl]ethan-1-amine (CAS 901273-26-5)
- 2-(1-(3-Chlorophenyl)-4,4-difluorocyclohexyl)acetic acid (CAS 2251053-46-8)
- 4,4-Diethoxy-1,1,1-trifluorobutan-2-one (CAS 333339-64-3)
- N-allyl-1-(4-nitrophenyl)piperidine-4-carboxamide (CAS 303144-45-8)
- [4-(4-methylphenyl)-2-pyridin-2-yl-1,3-thiazol-5-yl]acetic acid hydrobromide (CAS 1170198-01-2)
- 2-Bromo-[1,1'-biphenyl]-3-carboxylic acid (CAS 1049143-36-3)
- Tau Peptide (307-321) trifluoroacetate salt (CAS 330456-50-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com