4,6-Dimethoxy-2-(p-tolyl)pyrimidine CAS 77232-14-5

Purity 97%+In StockPharmaceutical Standards
CAS No.77232-14-5
Molecular FormulaC13H14N2O2
Molecular Weight230.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4,6-Dimethoxy-2-(p-tolyl)pyrimidine CAS 77232-14-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,6-Dimethoxy-2-(p-tolyl)pyrimidine.

4,6-Dimethoxy-2-(p-tolyl)pyrimidine (CAS 77232-14-5), molecular formula C13H14N2O2 and molecular weight 230.26 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4,6-Dimethoxy-2-(p-tolyl)pyrimidine (C13H14N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4,6-Dimethoxy-2-(p-tolyl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H14N2O2
Molecular Weight230.26 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1979
Nitrogen Atoms2

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Why CATO?