8-((3-Nitro-1H-1,2,4-triazol-1-yl)sulfonyl)quinoline CAS 77244-88-3
| CAS No. | 77244-88-3 |
| Molecular Formula | C11H7N5O4S |
| Molecular Weight | 305.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-((3-Nitro-1H-1,2,4-triazol-1-yl)sulfonyl)quinoline is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
8-((3-Nitro-1H-1,2,4-triazol-1-yl)sulfonyl)quinoline (CAS 77244-88-3), molecular formula C11H7N5O4S and molecular weight 305.27 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 8-((3-Nitro-1H-1,2,4-triazol-1-yl)sulfonyl)quinoline (C11H7N5O4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 305.27 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-((3-Nitro-1H-1,2,4-triazol-1-yl)sulfonyl)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7N5O4S |
| Molecular Weight | 305.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 2-{[2-ethyl-4-(trifluoromethyl)-2h-pyrazolo[3,4-b]pyridin-6-yl]sulfanyl}acetic acid (CAS 1018166-25-0)
- 6-Amino-1H-naphtho[1,2-d]imidazol-2(3H)-one (CAS 155137-75-0)
- 4-Chloro-6-ethoxy-2-phenylquinoline (CAS 860197-69-9)
- (2-((2,4-Dichlorobenzyl)oxy)-5-methylphenyl)methanol (CAS 1427013-19-1)
- Methyl 3-amino-3-(3-fluoro-4-methylphenyl)propanoate (CAS 1343342-53-9)
- 1-Cyclohexyl-3,3-dimethoxypropan-1-one (CAS 7014-88-2)
- 2-(1,1-Dioxidoisothiazolidin-2-yl)acetic acid (CAS 63459-24-5)
- Methyl 2-(2,5-dimethylphenyl)propanoate (CAS 99356-70-4)
- Piracetam EP Impurity 4 (CAS 22126-44-9)
- N-[4-[4-(3-Bromo-4-fluorophenyl)-5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl]-1,2,5-oxadiazol-3-yl]-2,2,2-trifluoroacetamide (CAS 914471-60-6)
- Pancreatic Polypeptide (bovine) (CAS 179986-89-1)
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