tert-Butyl 4-benzoylpiperazine-1-carboxylate CAS 77278-38-7
| CAS No. | 77278-38-7 |
| Molecular Formula | C16H22N2O3 |
| Molecular Weight | 290.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl 4-benzoylpiperazine-1-carboxylate.
tert-Butyl 4-benzoylpiperazine-1-carboxylate (CAS 77278-38-7), molecular formula C16H22N2O3 and molecular weight 290.36 g/mol, is a CATO reference standard with documented purity and traceability.
tert-Butyl 4-benzoylpiperazine-1-carboxylate (C16H22N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures tert-Butyl 4-benzoylpiperazine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H22N2O3 |
| Molecular Weight | 290.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl 2-(3-Amino-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)acetate (CAS 98626-45-0)
- tert-Butyl 4-benzyl-3-oxopiperazine-1-carboxylate (CAS 78551-60-7)
- Tert-butyl (s)-(1-benzoylpyrrolidin-3-yl)carbamate (CAS 335280-43-8)
- tert-Butyl 5-oxo-7-phenyl-1,4-diazepane-1-carboxylate (CAS 220898-16-8)
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- Tadalafil Impurity 147 (CAS 629652-68-2)
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