3-(Fluoromethyl)aniline CAS 456-46-2
| CAS No. | 456-46-2 |
| Molecular Formula | C7H8FN |
| Molecular Weight | 125.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 125.14 g/mol gives 3-(Fluoromethyl)aniline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(Fluoromethyl)aniline (CAS 456-46-2) is a high-purity analytical reference standard with the molecular formula C7H8FN and a molecular weight of 125.14 g/mol.
3-(Fluoromethyl)aniline (C7H8FN) contains a nitrile group, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8FN |
| Molecular Weight | 125.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoromethyl Standards
- 2-(Fluoromethyl)aniline (CAS 511230-96-9)
- 1-(Fluoromethyl)-3-methylbenzene (CAS 456-44-0)
- 4-(Fluoromethyl)phenol (CAS 62037-85-8)
- 2-(Fluoromethyl)pyrimidin-4-amine (CAS 16097-51-1)
- 2-(Fluoromethyl)pyrimidin-5-ol (CAS 1391733-75-7)
- 5-(Fluoromethyl)furan-2-carbaldehyde (CAS 94043-06-8)
- 3,3-Bis(fluoromethyl)oxetane (CAS 338-61-4)
- 6-(Fluoromethyl)-3-azabicyclo[4.1.0]heptane (CAS 1258639-99-4)
Recommended Standards
- 2-Fluoro-5-methylaniline (CAS 452-84-6)
- 3-Ethyl-5-fluoropyridine (CAS 2089319-08-2)
- 2-Fluoro-4-methylaniline, 97% (CAS 452-80-2)
- 3-Fluoro-2,6-dimethylpyridine (CAS 766-62-1)
- 4-amino-2-methoxypyrimidine-5-carbaldehyde (CAS 26664-09-5)
- 3,4-Diamino-n-methylbenzene-1-sulfonamide (CAS 125106-42-5)
- Benzil (CAS 134-81-6)
- Crizotinib Impurity 43 (CAS CATO-C4X-102543)
- 2-Fluro-6-isopropoxyphenol (CAS 1055315-24-6)
- 1-Methyl-2-(4-(trifluoromethyl)phenyl)piperazine (CAS 1380897-78-8)
- ethyl 2-(2-oxoazepan-3-yl)acetate (CAS 831-32-3)
- 1-(5-(tert-Butylthio)pyridin-2-yl)piperazine (CAS 1355208-08-0)
- Octafluorocyclopentene (CAS 559-40-0)
- Neuropeptide Y (porcine) trifluoroacetate salt (CAS 83589-17-7)
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