Lidocaine EP Impurity D(HCl) CAS 7729-94-4
| CAS No. | 7729-94-4 |
| Molecular Formula | C12H18N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Lidocaine EP Impurity D(HCl) (C12H18N2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Lidocaine EP Impurity D(HCl) (CAS 7729-94-4, C12H18N2OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lidocaine EP Impurity D(HCl) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H18N2O HCl |
| Molecular Weight | 242.75 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Lidocaine Standards
- Lidocaine EP Impurity J HCl (CAS 1012864-23-1)
- Lidocaine Impurity 70 HCl (CAS 101651-71-2)
- Lidocaine Impurity 57 (CAS 102878-74-0)
- Lidocaine Impurity 19 (CAS 108-69-0)
- Lidocaine EP Impurity H (CAS 1131-01-7)
- Lidocaine EP Impurity E Hydrochloride (CAS 1135231-62-7)
- Lidocaine-d10 Hydrochloride (CAS 1189959-13-4)
- Lidocaine EP Impurity D-d6 (CAS 1216698-89-3)
Recommended Standards
- Levodropropizine N-Oxide Impurity 3 (CAS 152237-40-6)
- Blonanserin Impurity 42 (CAS CATO-C4X-111042)
- Omeprazole Impurity 26 (CAS 142885-92-5)
- Celecoxib Impurity 25 (CAS CATO-C4X-104325)
- 3-(Aziridin-1-yl)phenol (CAS 500284-15-1)
- 2-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-4-(1H-pyrrol-1-yl)isoindoline-1,3-dione (CAS 339101-76-7)
- 6-Chloro-3-(difluoromethyl)-2-methoxypyridine (CAS 1805008-40-5)
- 4-(6-Chloro-pyridazin-3-ylmethyl)-1-isopropyl-azepane (CAS 1361114-45-5)
- 2-(1H-imidazol-4-yl)ethan-1-ol (CAS 872-82-2)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com