Ethyl 4-chloro-2,6-difluorobenzoate CAS 773139-38-1
| CAS No. | 773139-38-1 |
| Molecular Formula | C9H7ClF2O2 |
| Molecular Weight | 220.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 220.60 g/mol gives Ethyl 4-chloro-2,6-difluorobenzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 4-chloro-2,6-difluorobenzoate (CAS 773139-38-1) is a high-purity analytical reference standard with the molecular formula C9H7ClF2O2 and a molecular weight of 220.60 g/mol.
Ethyl 4-chloro-2,6-difluorobenzoate (C9H7ClF2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H7ClF2O2 |
| Molecular Weight | 220.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
Related Ethyl Standards
- Ethyl 3-chloro-2,4-difluorobenzoate (CAS 1097886-66-2)
- 1-(4-Chloro-2-(difluoromethoxy)phenyl)ethanone (CAS 110760-05-9)
- 2-Chloro-1-(4-(difluoromethoxy)phenyl)ethanone (CAS 1214341-01-1)
- Ethyl 5-chloro-2,3-difluorobenzoate (CAS 1214361-29-1)
- 2-Chloro-1-(3-(difluoromethoxy)phenyl)ethan-1-one (CAS 1214377-17-9)
- Ethyl 5-chloro-2,4-difluorobenzoate (CAS 1239592-10-9)
- Methyl 2-chloro-2-(2,4-difluorophenyl)acetate (CAS 1247585-58-5)
- 1-[5-chloro-2-(difluoromethoxy)phenyl]ethan-1-one (CAS 1250157-06-2)
Recommended Standards
- Ethyl 3-chloro-2,6-difluorobenzoate (CAS 773135-47-0)
- Sitagliptin Impurity 118 (CAS 1261633-32-2)
- Ethyl 2-chloro-3,6-difluorobenzoater (CAS 773135-52-7)
- Tegoprazan Impurity 10 (CAS CATO-C4X-229710)
- 1-(Difluoromethyl)-1H-indole (CAS 748785-26-4)
- 1-(4-Bromophenyl)-2-methylpropan-1-amine (CAS 785762-36-9)
- 1-(3-Methyl-1-propyl-1H-pyrazol-4-yl)-N-((1-methyl-1H-pyrrol-2-yl)methyl)methanamine hydrochloride (CAS 1855948-39-8)
- 3-tert-Butyldimethylsilyloxy Pregnenolone (CAS 58701-45-4)
- 2,2-Diallylpent-4-en-1-amine (CAS 928836-00-4)
- 2-(3-(Tert-butyl)-1-methyl-1h-pyrazol-4-yl)ethan-1-amine (CAS 1483887-94-0)
- Ethyl 2-fluoro-4-(4-nitrophenyl)benzoate (CAS 1365272-65-6)
- tert-Butyl 3-(3,6-difluoro-2-methoxyphenyl)-3-hydroxyazetidine-1-carboxylate (CAS 1872383-15-7)
- 6,6-Difluorospiro[3.3]heptan-2-amine (CAS 1354952-13-8)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
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