Famotidine impurity 67 CAS 77345-71-2
| CAS No. | 77345-71-2 |
| Molecular Formula | C6H6N2O4 |
| Molecular Weight | 170.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Famotidine impurity 67 (CAS 77345-71-2), a pharmacopoeial impurity reference standard (molecular formula C6H6N2O4, MW 170.12 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Famotidine impurity 67 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 170.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Famotidine impurity 67 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6N2O4 |
| Molecular Weight | 170.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 2 |
Related Famotidine Standards
- Famotidine Impurity 80 (CAS CATO-C4X-139280)
- Famotidine Impurity C22 (CAS 86794-42-5)
- Famotidine Impurity 81 (CAS CATO-C4X-139281)
- Famotidine impurity 75 (CAS 90924-16-6)
- Famotidine Impurity 3 (CAS 13598-81-7)
- Famotidine Impurity 41 (CAS CATO-C4X-139241)
- Famotidine impurity 74 (CAS 90224-97-8)
- Famotidine impurity 69 (CAS 850864-53-8)
Recommended Standards
- 2-Carboxy-5-methylpyrazine 1,4-dioxide (CAS 2734844-49-4)
- Phloroglucinol Impurity 32 (CAS 83-30-7)
- 439109-81-6 6-Hydroxy-1-methyl-2-oxo-1,2-dihydro-4-pyrimidinecarboxylic acid MFCD00244509 (CAS 439109-81-6)
- Gallic Acid (CAS 149-91-7)
- Promethazine Impurity 26 (CAS 15521-18-3)
- Sildenafil Impurity 67 (CAS 3312-58-1)
- Artemisinin Impurity 20 (CAS CATO-C4X-201220)
- 1-Methyl-9-phenoxyacridine (CAS 61078-23-7)
- (1-Methyl-2,3-dihydro-1h-indol-5-yl)(4-methylpiperazin-1-yl)acetonitrile (CAS 1170211-74-1)
- 4-Ethoxybutan-2-ol (CAS 53892-34-5)
- Bis(4-Tert-octylphenyl)amine (CAS 15721-78-5)
- N-Butyl-3-ethoxy-2-(2-methoxyethyl)-2H-indazole-6-carboxamide (CAS 919108-51-3)
- 1,3,7-Trimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purine-8-carboxylic acid (CAS 648425-51-8)
- Semaglutide impurity 97 (CAS CATO-C4X-222697)
Why CATO?
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