2-Chloro-1-(4-(pyridin-2-yl)piperazin-1-yl)propan-1-one CAS 77368-17-3
| CAS No. | 77368-17-3 |
| Molecular Formula | C12H16ClN3O |
| Molecular Weight | 253.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 253.73 g/mol gives 2-Chloro-1-(4-(pyridin-2-yl)piperazin-1-yl)propan-1-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Chloro-1-(4-(pyridin-2-yl)piperazin-1-yl)propan-1-one (CAS 77368-17-3) is a high-purity analytical reference standard with the molecular formula C12H16ClN3O and a molecular weight of 253.73 g/mol.
The molecular framework of 2-Chloro-1-(4-(pyridin-2-yl)piperazin-1-yl)propan-1-one (C12H16ClN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-1-(4-(pyridin-2-yl)piperazin-1-yl)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H16ClN3O |
| Molecular Weight | 253.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
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- 1-{2-[2-(6-Chloro-pyridazin-3-yl)-ethyl]-pyrrolidin-1-yl}-ethanone (CAS 1316218-48-0)
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Recommended Standards
- 2-Amino-1-[4-(4-chlorophenyl)piperazin-1-yl]ethan-1-one (CAS 770699-74-6)
- 2-Chloro-4-(piperidin-1-yl)benzohydrazide (CAS 952183-28-7)
- 2-Amino-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one (CAS 938337-99-6)
- 2-Chloro-6-methyl-3-phenylquinoline (CAS 284664-59-1)
- 4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 1256358-95-8)
- Ethyl 4-amino-7-bromoquinoline-3-carboxylate (CAS 1253420-35-7)
- Glycylproline (CAS 118203-80-8)
- Hydroxychloroquine Impurity 73 (CAS CATO-C4X-183573)
- 4-(Chloromethyl)-1-(2,3-dimethylphenyl)-1H-1,2,3-triazole (CAS 1249623-34-4)
- 3-Isopropoxypropane-1,2-diol (CAS 17226-43-6)
- 2-(2,2,2-Trifluoroethoxy)pyrimidine-5-carbaldehyde (CAS 944904-99-8)
- (2R,4S)-4-[(3-Carboxy-1-oxopropyl)amino]-4-[(p-phenylphenyl)methyl]-2-methylbutanoic acid ethyl ester (2R,4S)-5-(Biphenyl-4-yl)-4-[(3-carboxypropionyl)amino]-2-methylpentanoic acid ethyl ester 1032350-13-2 4-[[(2S,4R)-5-Ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid calcium salt 4-{[(2S,4R)-1-(4-Biphenylyl)-5-ethoxy-4-methyl-5-oxo-2-pentanyl]amino}-4-oxobutanoic acid AHU377 calcium salt MK-2206 2HCl (CAS 1032350-13-2)
- 2,4-Dichloro-5-(difluoromethyl)pyrimidine (CAS 1807617-94-2)
- RGD-targeted Proapoptotic Peptide trifluoroacetate salt (CAS 2243207-09-0)
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