Ethyl 4-(2-chloropropanoyl)piperazine-1-carboxylate CAS 77368-22-0

Purity 97%+In StockPharmaceutical Standards
CAS No.77368-22-0
Molecular FormulaC10H17ClN2O3
Molecular Weight248.71 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 4-(2-chloropropanoyl)piperazine-1-carboxylate CAS 77368-22-0 chemical structure

Description

The occurrence of Ethyl 4-(2-chloropropanoyl)piperazine-1-carboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Ethyl 4-(2-chloropropanoyl)piperazine-1-carboxylate (CAS 77368-22-0), molecular formula C10H17ClN2O3 and molecular weight 248.71 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Ethyl 4-(2-chloropropanoyl)piperazine-1-carboxylate (C10H17ClN2O3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Ethyl 4-(2-chloropropanoyl)piperazine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H17ClN2O3
Molecular Weight248.71 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1979
Halogen ContentCl-containing
Nitrogen Atoms2

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