3-(2,5-Dichlorophenyl)-1-methyldihydropyrimidine-2,4(1H,3H)-dione CAS 77385-16-1
| CAS No. | 77385-16-1 |
| Molecular Formula | C11H10Cl2N2O2 |
| Molecular Weight | 273.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 273.12 g/mol gives 3-(2,5-Dichlorophenyl)-1-methyldihydropyrimidine-2,4(1H,3H)-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(2,5-Dichlorophenyl)-1-methyldihydropyrimidine-2,4(1H,3H)-dione (CAS 77385-16-1), molecular formula C11H10Cl2N2O2 and molecular weight 273.12 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-(2,5-Dichlorophenyl)-1-methyldihydropyrimidine-2,4(1H,3H)-dione (C11H10Cl2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 273.12 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10Cl2N2O2 |
| Molecular Weight | 273.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorophenyl Standards
- 1-(2,4-dichlorophenyl)-3-methyl-hexahydropyrimidine-2,4-dione (CAS 101394-17-6)
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- N-(2,5-Dichlorophenyl)-5-oxopyrrolidine-2-carboxamide (CAS 4108-16-1)
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Recommended Standards
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- 3-(3-Bromo-phenoxy)-2,2-dimethyl-propionic acid (CAS 938314-53-5)
- Methyl (2S,4R)-4-Hydroxy-1-[(R)-1-phenylethyl]piperidine-2-carboxylate (CAS 1103929-22-1)
- 4-Chloro-1-pentyl-1h-pyrazol-3-amine (CAS 1343935-69-2)
- 2-Oxo-2-((1-phenylethyl)amino)ethyl 5-methylthiophene-2-carboxylate (CAS 488754-75-2)
- 3-(4-Chloro-phenyl)-6-phenyl-3,4-dihydro-1H-[1,3,5]triazine-2-thione (CAS 501106-00-9)
- Didodecyldimethylammonium Bromide (CAS 3282-73-3)
- Methyl 2-amino-5-thiomorpholinobenzoate (CAS 773071-98-0)
- 2-(1H-Pyrrol-1-yl)isoindoline-1,3-dione (CAS 885-12-1)
- 5-Chloro-2-((3-phenylpropyl)amino)benzoic acid (CAS 1406474-20-1)
- 7-bromo-8-fluoro-3-methyl-3,4-dihydro-1H-quinoxalin-2-one (CAS 2756334-24-2)
- Fragment-[7-31]-Liraglutide (CAS CATO-C4X-199239)
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