1-(((3,4-Dichlorophenyl)amino)methyl)pyrrolidine-2,5-dione CAS 5303-32-2
| CAS No. | 5303-32-2 |
| Molecular Formula | C11H10Cl2N2O2 |
| Molecular Weight | 273.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(((3,4-Dichlorophenyl)amino)methyl)pyrrolidine-2,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(((3,4-Dichlorophenyl)amino)methyl)pyrrolidine-2,5-dione (CAS 5303-32-2) is a high-purity analytical reference standard with the molecular formula C11H10Cl2N2O2 and a molecular weight of 273.12 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 1-(((3,4-Dichlorophenyl)amino)methyl)pyrrolidine-2,5-dione is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 273.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H10Cl2N2O2 |
| Molecular Weight | 273.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorophenyl Standards
- 1-(2,4-dichlorophenyl)-3-methyl-hexahydropyrimidine-2,4-dione (CAS 101394-17-6)
- 3-(2,5-Dichlorophenyl)-1-methyldihydropyrimidine-2,4(1H,3H)-dione (CAS 77385-16-1)
- N-(2,5-Dichlorophenyl)-5-oxopyrrolidine-2-carboxamide (CAS 4108-16-1)
- N-(3,4-Dichlorophenyl)-5-oxoprolinamide (CAS 4108-15-0)
- 5-(2,5-Dichlorophenyl)thiophene-2-carboxylic acid (CAS 1007089-03-3)
- 5-(3,5-dichlorophenyl)thiophene-2-carboxylic acid (CAS 1099660-24-8)
- 6-(2,4-Dichlorophenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 1465572-32-0)
- 6-(3,4-Dichlorophenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 1489124-24-4)
Recommended Standards
- 2-(Bromo(4-methoxyphenyl)methyl)-1,3-dioxolane (CAS 1956386-63-2)
- 10-Bromophenanthren-9-ol (CAS 4120-76-7)
- Methyl 2-(4-bromo-5-(hydroxymethyl)-2-methylphenyl)acetate (CAS 1956370-75-4)
- 2-(2-Bromophenoxy)-3-methylbutanoic acid (CAS 938321-20-1)
- Bis(1,3-dimethylcyclopenta-2,4-dien-1-yl)zirconium(IV) chloride (CAS 119445-92-0)
- N-(3,4-dimethoxyphenethyl)tetrahydrothiophen-3-amine (CAS 415969-38-9)
- Methyl[(4-methyl-2-propyl-1,3-thiazol-5-yl)methyl]amine (CAS 1250562-06-1)
- 4-Benzhydryl-N-(2-fluorophenyl)piperazine-1-carboxamide (CAS 893340-18-6)
- 2,5-Dichloro-3-(difluoromethoxy)anisole (CAS 1806348-66-2)
- Ceftolozane Impurity 32 (CAS CATO-C4X-240632)
- Mianserin Impurity 91 (CAS 1192015-20-5)
- 1,6-Dimethyl-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde (CAS 1368175-67-0)
- Ethyl 2,5-dimethyl-1H-pyrrole-3-carboxylate (CAS 2199-52-2)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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