Methyl 2,3-difluoro-4-methylbenzoate CAS 773874-06-9
| CAS No. | 773874-06-9 |
| Molecular Formula | C9H8F2O2 |
| Molecular Weight | 186.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Methyl 2,3-difluoro-4-methylbenzoate (CAS 773874-06-9), molecular formula C9H8F2O2 and molecular weight 186.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 2,3-difluoro-4-methylbenzoate (C9H8F2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H8F2O2 |
| Molecular Weight | 186.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
Related Methyl Standards
- 2-(2,4-Difluoro-3-methylphenyl)acetic acid (CAS 1000545-11-8)
- 1-(2,5-Difluoro-4-methoxyphenyl)ethanone (CAS 1010800-85-7)
- 2,2-Difluoro-2-(m-tolyl)acetic acid (CAS 1038247-17-4)
- 2,2-Difluoro-1-(4-methoxyphenyl)ethanone (CAS 114829-07-1)
- Methyl 2,4-difluoro-5-methylbenzoate (CAS 1162674-66-9)
- 1-(2,6-Difluoro-3-methoxyphenyl)ethan-1-one (CAS 1206593-23-8)
- Methyl 2,4-difluoro-3-methylbenzoate (CAS 1206675-31-1)
- Methyl 4,5-difluoro-2-methylbenzoate (CAS 1245515-60-9)
Recommended Standards
- Methyl 2-(3,5-difluorophenyl)acetate (CAS 210530-70-4)
- Methyl 2,4-Difluorophenylacetate (CAS 95299-17-5)
- Methyl 2-(3,4-difluorophenyl)acetate (CAS 210530-71-5)
- Methyl 2,5-difluoro-3-methylbenzoate (CAS 952479-99-1)
- n-(2-Methylcyclohexyl)-3-(pyrrolidin-1-yl)aniline (CAS 1184268-55-0)
- methyl 6-(thiophen-3-ylformamido)hexanoate (CAS 1153551-91-7)
- 5-(2,5-Difluorophenoxy)pentanenitrile (CAS 1406929-37-0)
- 2-((4-Isopropylphenoxy)methyl)oxirane (CAS 2210-72-2)
- (E)-N-(4-Chlorophenyl)-N'-(propan-2-yl)pyridine-3-carboximidamide (CAS 338408-32-5)
- 2-{4-aminopyrrolo[2,1-f][1,2,4]triazin-2-yl}acetamide (CAS 2091629-13-7)
- Benzene, 1,1'-(dichlorosilylene)bis-, polymer with dichlorodimethylsilane, trichloromethylsilane and (trichlorosilyl)benzene (CAS 28630-33-3)
- 2-(4-((1H-1,2,4-Triazol-1-yl)methyl)phenyl)-N-isopentyl-1,3-dioxoisoindoline-5-carboxamide (CAS 1081113-71-4)
- 5-(Bromomethyl)-2-iodophenol (CAS 1823881-56-6)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com