Methyl 4-(difluoromethoxy)-3-methoxybenzoate CAS 773874-12-7
| CAS No. | 773874-12-7 |
| Molecular Formula | C10H10F2O4 |
| Molecular Weight | 232.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 232.18 g/mol gives Methyl 4-(difluoromethoxy)-3-methoxybenzoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Methyl 4-(difluoromethoxy)-3-methoxybenzoate (CAS 773874-12-7), a certified reference material (molecular formula C10H10F2O4, MW 232.18 g/mol) for analytical method development and quality control.
Structurally, Methyl 4-(difluoromethoxy)-3-methoxybenzoate (C10H10F2O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 232.18 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 4-(difluoromethoxy)-3-methoxybenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10F2O4 |
| Molecular Weight | 232.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
Related Methyl Standards
- 4-(Difluoromethoxy)-3-ethoxybenzoic acid (CAS 162401-63-0)
- 2-[3-(difluoromethoxy)-4-methoxyphenyl]acetic acid (CAS 776324-86-8)
- 4-(Difluoromethoxy)-3,5-dimethoxybenzaldehyde (CAS 446270-61-7)
- 4-(Difluoromethoxy)-3-methoxybenzohydrazide (CAS 446267-81-8)
- 2-(Difluoromethoxy)-3-fluorocinnamic acid (CAS 1262011-98-2)
- 2-(Difluoromethoxy)-4-fluorocinnamic acid (CAS 1262012-43-0)
- 2-(Difluoromethoxy)-6-fluorocinnamic acid (CAS 1262012-57-6)
- 2-(Difluoromethoxy)-5-fluorocinnamic acid (CAS 1262014-14-1)
Recommended Standards
- Methyl 3-(2,2-difluoroethoxy)-5-hydroxybenzoate (CAS 2597914-28-6)
- Methyl 4-(difluoromethyl)-5-hydroxy-2-methoxybenzoate (CAS 2385870-77-7)
- Methyl 2,6-difluoro-3,5-dimethoxybenzoate (CAS 651734-55-3)
- 4-Imino-1,4-dihydroquinoline-3,6-dicarboxylic acid (CAS 1011407-10-5)
- (6-Amino-5-bromo-4-(difluoromethyl)pyridin-3-yl)methanol (CAS 1805334-95-5)
- 2-(4-Bromo-3-(difluoromethyl)-6-iodopyridin-2-yl)acetonitrile (CAS 1805244-80-7)
- 8-Methylbenz[a]anthracene-d14 (CAS 1794940-15-0)
- Cbz-L-tert-Leucine isopropylamine salt (CAS 1621085-33-3)
- Tert-butyldimethyl((4,5,6,7-tetrahydrobenzofuran-7-yl)oxy)silane (CAS 191480-99-6)
- Methyl 4-chloro-1-ethyl-1H-pyrazole-5-carboxylate (CAS 1692714-97-8)
- 2-(butan-2-ylamino)acetic acid hydrochloride (CAS 6939-21-5)
- 5-(3,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-amine (CAS 19949-29-2)
- 2-[(5-chloro-2-fluorophenyl)formamido]-3-hydroxybutanoic acid (CAS 1396969-18-8)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
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