5-Bromo-N-isopropylpyrimidin-2-amine CAS 77476-95-0
| CAS No. | 77476-95-0 |
| Molecular Formula | C7H10BrN3 |
| Molecular Weight | 216.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Bromo-N-isopropylpyrimidin-2-amine (C7H10BrN3) is characterized by a nitrile group, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-Bromo-N-isopropylpyrimidin-2-amine (CAS 77476-95-0), molecular formula C7H10BrN3 and molecular weight 216.08 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Bromo-N-isopropylpyrimidin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H10BrN3 |
| Molecular Weight | 216.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 5-Bromo-N-ethyl-N-methylpyrazin-2-amine (CAS 959238-79-0)
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- 6-Amino-2-bromo-3,4-dimethylphenol (CAS 854663-56-2)
- 4-((4-(Dimethylamino)benzylidene)amino)-3-(2-methoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478256-88-1)
- tert-Butyl 2-((2-chloro-N-ethylacetamido)methyl)piperidine-1-carboxylate (CAS 1353943-62-0)
- 4,6-Dichloro-2-(ethoxymethyl)pyrimidine (CAS 3122-82-5)
- (S)-tert-Butyl sec-butylcarbamate (CAS 1932100-42-9)
- 4-(3,5-dimethylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride (CAS 1427380-83-3)
- 1-(3,3-difluorocyclobutyl)ethan-1-one (CAS 1621223-57-1)
- (Z)-3-((4-Bromophenyl)(4-(methylsulfonyl)phenyl)methylene)dihydrofuran-2(3H)-one (CAS 197438-73-6)
- 1-(5-(Trifluoromethoxy)pyridin-3-yl)ethan-1-one (CAS 1060815-11-3)
- 4-Ethyl-2-(3-methyl-4-nitrophenyl)morpholine (CAS 1010384-74-3)
- Semaglutide Impurity 133 (CAS CATO-C4X-2226133)
Why CATO?
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