6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinolin-5-amine CAS 77498-30-7
| CAS No. | 77498-30-7 |
| Molecular Formula | C10H13FN2 |
| Molecular Weight | 180.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinolin-5-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinolin-5-amine (CAS 77498-30-7) is a high-purity analytical reference standard with the molecular formula C10H13FN2 and a molecular weight of 180.22 g/mol.
The molecular framework of 6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinolin-5-amine (C10H13FN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H13FN2 |
| Molecular Weight | 180.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- Ticarcillin EP Impurity A (CAS 36041-93-7)
- 2,5-Dioxopyrrolidin-1-yl cinnamate (CAS 23776-87-6)
- 2-(2-Fluorobenzyl)pyrrolidine (CAS 383127-84-2)
- Des-5’-chloro-4-fluorobenzyl Mosapride (CAS 170799-30-1)
- BIBR 1532 (CAS 321674-73-1)
- Abiraterone Impurity 50 (CAS CATO-C4X-107050)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com