Dibenzo[b,e][1,4]dioxine-2,8-diol CAS 775537-59-2
| CAS No. | 775537-59-2 |
| Molecular Formula | C12H8O4 |
| Molecular Weight | 216.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Dibenzo[b,e][1,4]dioxine-2,8-diol (CAS 775537-59-2), molecular formula C12H8O4 and molecular weight 216.19 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Dibenzo[b,e][1,4]dioxine-2,8-diol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 216.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Dibenzo[b,e][1,4]dioxine-2,8-diol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8O4 |
| Molecular Weight | 216.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
Related Dibenzo Standards
- Dibenzo[b,e][1,4]dioxine-1,2-diol (CAS 71866-41-6)
- 2H-Dibenzo[e,g]isoindole (CAS 235-93-8)
- Dibenzo[d,f]indole (CAS 7018-30-6)
- Dibenzo[b,d]thiophene-3,7-diamine (CAS 41738-64-1)
- Dibenzo[b,d]thiophen-4-ylmethanol (CAS 19806-49-6)
- Dibenzo[b,e][1,4]dioxin-2-ylmethanol (CAS 42039-85-0)
- Dibenzo[b,d]furan-3,7-dicarbonitrile (CAS 33763-36-9)
- 5H-Dibenzo[b,f]azepine-5-carbonitrile (CAS 42787-75-7)
Recommended Standards
- Ethyl 5-amino-3-(2-hydroxyethoxy)isoxazole-4-carboxylate (CAS 446276-12-6)
- Benzo[d][1,3]dioxol-5-yl(furan-2-yl)methanone (CAS 868944-60-9)
- Methyl 1,4-dioxo-1,4-dihydronaphthalene-2-carboxylate (CAS 83575-14-8)
- 7-Formyl-3-hydroxy-2-naphthoic acid (CAS 503827-81-4)
- 1,2,3,4,6,7-Hexahydrophenazine (CAS 112448-71-2)
- (4-(4-Fluorobenzo[d]thiazol-2-yl)piperazin-1-yl)(isoxazol-5-yl)methanone (CAS 941869-30-3)
- 3-(iodomethyl)tetrahydropyran (CAS 32730-60-2)
- 2,3-Dichloro-4-(difluoromethyl)-6-iodopyridine (CAS 1804449-18-0)
- Phytomenadione/Vitamin K1 Impurity 133 (CAS 854039-21-7)
- 3-(4-((5-Chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)methoxy)phenyl)-2-methylpropanoic acid (CAS 1234841-58-7)
- 2-Isopropylcyclohexan-1-amine (CAS 6850-64-2)
- Ethyl 2-chloro-4-methyl-3-oxopentanoate (CAS 35391-60-7)
- (Z)-2-amino-N'-(2,4-dichlorobenzoyl)-4-methoxynicotinohydrazonamide (CAS 338773-80-1)
- (Gly1,Ser3·22,Gln?·3?,Thr?,Arg1?,Tyr21,Ala23·31,Aib32)-Pancreatic Polypeptide (human) (CAS 313988-89-5)
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