Ethyl 2,4-dichloro-5,6-dimethylnicotinate CAS 77629-52-8
| CAS No. | 77629-52-8 |
| Molecular Formula | C10H11Cl2NO2 |
| Molecular Weight | 248.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 2,4-dichloro-5,6-dimethylnicotinate (CAS 77629-52-8), molecular formula C10H11Cl2NO2 and molecular weight 248.11 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C10H11Cl2NO2, Ethyl 2,4-dichloro-5,6-dimethylnicotinate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 248.11 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11Cl2NO2 |
| Molecular Weight | 248.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 4,6-Dichloro-2-(diethylamino)pyrimidine-5-carbaldehyde (CAS 111953-91-4)
- Ethyl 4,6-dichloro-2-ethylnicotinate (CAS 1420670-53-6)
- 2-(4,6-Dichloro-2,3-dimethylphenoxy)acetamide (CAS 1706438-58-5)
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Recommended Standards
- 6,9-Dichloroacridine (CAS 35547-70-7)
- Ethyl 2-[(3,5-dichlorophenyl)amino]acetate (CAS 501008-39-5)
- Baclofen EP Impurity F (CAS 4846-95-1)
- Ethyl 2-amino-2-(2,3-dichlorophenyl)acetate (CAS 500772-54-3)
- Selenazofurin (CAS 83705-13-9)
- N-(5-Amino-2-fluorophenyl)-2-[2-(tert-butyl)-phenoxy]acetamide (CAS 1020053-99-9)
- 3-(2-Chlorophenyl)-2-(4-chlorophenyl)-3-oxopropanenitrile (CAS 96514-71-5)
- Ro 4929097 (CAS 847925-91-1)
- tert-Butyl (3,5-dimethyl-4H-1,2,4-triazol-4-yl)carbamate (CAS 187145-70-6)
- (2R,3S,5R)-5-(6-Amino-2-hydrazinyl-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 1000296-26-3)
- 4-Cyclopropoxy-2-isopropoxy-3-(methylthio)pyridine (CAS 1243379-81-8)
- 1-(6-Methoxypyridin-2-yl)cyclopropan-1-amine (CAS 1060806-97-4)
- 1-((2-Nitrophenyl)sulfonyl)piperidin-4-one (CAS 267666-09-1)
- Fibronectin Adhesion-Promoting Peptide (CAS 125720-21-0)
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