Amicoumacin B CAS 77674-99-8
| CAS No. | 77674-99-8 |
| Molecular Formula | C20H28N2O8 |
| Molecular Weight | 424.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Amicoumacin B is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Amicoumacin B (CAS 77674-99-8), a certified reference material (molecular formula C20H28N2O8, MW 424.44 g/mol) for analytical method development and quality control.
The molecular framework of Amicoumacin B (C20H28N2O8) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Amicoumacin B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H28N2O8 |
| Molecular Weight | 424.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 2 |
Recommended Standards
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- 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one (CAS 381702-30-3)
- Diethyl 1,1'-(hexane-1,6-diyl)bis(4,5-dioxopyrrolidine-3-carboxylate) (CAS 7596-14-7)
- tert-Butyl 5-methyl-2,7-diazaspiro[3.5]nonane-7-carboxylate (CAS 1899106-63-8)
- N-(3-Aminophenyl)-4-fluorobenzenesulfonamide (CAS 436089-66-6)
- 1,2-Di(1-naphthyl)ethane (CAS 15374-45-5)
- 2-(Aminooxy)-1-(4-phenylpiperazin-1-yl)ethan-1-one hydrochloride (CAS 275374-83-9)
- [(2-cyanoethyl)(methyl)carbamoyl]formic acid (CAS 1156077-63-2)
- 2-Methyl-3'-(trifluoromethyl)-1,1'-biphenyl (CAS 791077-99-1)
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- Furan-2-ylmethyl butyrate (CAS 623-21-2)
- 2-(Cyclopropyl(4-methylbenzyl)amino)ethanol (CAS 1249264-80-9)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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