N-(5,5-Dimethyl-2-Oxooxolan-3-yl-4-(Trifluoromethyl)Benzamide CAS 77694-32-7
| CAS No. | 77694-32-7 |
| Molecular Formula | C14H14F3NO3 |
| Molecular Weight | 301.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(5,5-Dimethyl-2-Oxooxolan-3-yl-4-(Trifluoromethyl)Benzamide.
N-(5,5-Dimethyl-2-Oxooxolan-3-yl-4-(Trifluoromethyl)Benzamide (CAS 77694-32-7) is a high-purity analytical reference standard with the molecular formula C14H14F3NO3 and a molecular weight of 301.26 g/mol.
The molecular framework of N-(5,5-Dimethyl-2-Oxooxolan-3-yl-4-(Trifluoromethyl)Benzamide (C14H14F3NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N-(5,5-Dimethyl-2-Oxooxolan-3-yl-4-(Trifluoromethyl)Benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14F3NO3 |
| Molecular Weight | 301.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- Ethyl 2-(3,6-dimethyl-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1011370-71-0)
- Dimethyl 5-oxo-5,6-dihydropyrazolo[1,5-c]quinazoline-1,2-dicarboxylate (CAS 41940-24-3)
- N-(5-(1,3-Dimethyl-1H-pyrazol-5-yl)-1,3,4-oxadiazol-2-yl)-3-fluorobenzamide (CAS 1170049-33-8)
- N-(5-(1,3-Dimethyl-1H-pyrazol-5-yl)-1,3,4-oxadiazol-2-yl)-2-fluorobenzamide (CAS 1171368-15-2)
- 1,2-Dimethyl-4-oxo-6-(trifluoromethoxy)-1,4-dihydroquinoline-3-carboxylic acid (CAS 1958082-61-5)
- N-(5-(1,3-Dimethyl-1H-pyrazol-5-yl)-1,3,4-oxadiazol-2-yl)-1-ethyl-1H-pyrazole-3-carboxamide (CAS 1169972-71-7)
- (E)-4-((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino)-4-oxobut-2-enoic acid (CAS 649553-97-9)
- 1,3-Dimethyl 2-(2-amino-4-methanesulfonylphenyl)propanedioate (CAS 1373232-81-5)
Recommended Standards
- ethyl 2-[(ethoxycarbonyl)amino]-3,3,3-trifluoro-2-isopropoxypropanoate (CAS 256332-88-4)
- Sulphan Blue Impurity 2 (CAS 911304-76-2)
- Ethyl (2E)-4,4,4-trifluoro-3-[(4-methylphenyl)formamido]but-2-enoate (CAS 400087-75-4)
- tert-Butyl 3-(6-formyl-5-(trifluoromethyl)pyridin-3-yl)acrylate (CAS 2851876-24-7)
- 1-(6-Hydroxy-3-methylbenzofuran-7-yl)ethanone (CAS 41598-31-6)
- 2-Chloro-N-(7-methyl-9-oxo-9H-thioxanthen-2-yl)benzamide (CAS 860610-00-0)
- 1-[(4-bromophenyl)methyl]piperazin-2-one hydrochloride (CAS 2060052-87-9)
- 1-(7,7-Dimethyl-2-oxobicyclo[2.2.1]Heptan-1-yl)-N-(3-fluorophenyl)methanesulfonamide (CAS 453582-61-1)
- 2-Methyl-1-(phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 1014613-31-0)
- 2-methyl-3H-imidazo[4,5-b]pyridine-5-carboxylic acid (CAS 1304788-07-5)
- 2-(6-Bromopyridin-2-yl)-2-methylpropan-1-ol (CAS 955369-68-3)
- 2-(6-Methoxy-4-methylpyridin-2-yl)acetic acid (CAS 1393530-53-4)
- Tolvaptan Impurity 72 (CAS CATO-C4X-195572)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com