Hydrocortisone Impurity 43 CAS 7780-63-4
| CAS No. | 7780-63-4 |
| Molecular Formula | C25H32O6 |
| Molecular Weight | 428.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Hydrocortisone Impurity 43 (CAS 7780-63-4, C25H32O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Hydrocortisone Impurity 43 (C25H32O6) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Hydrocortisone Impurity 43 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H32O6 |
| Molecular Weight | 428.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Hydrocortisone Standards
- Hydrocortisone Impurity 28 (CAS CATO-C4X-140128)
- Hydrocortisone Impurity 24 (CAS CATO-C4X-140124)
- Hydrocortisone 21-Butyrate (CAS 6677-99-2)
- Hydrocortisone Impurity 58 (CAS CATO-C4X-140158)
- Hydrocortisone Butyrate (CAS 13609-67-1)
- Hydrocortisone Impurity 70 (CAS 116816-20-7)
- Hydrocortisone 17-Propionate (CAS 65980-97-4)
- Hydrocortisone 21-Propionate (CAS 6677-98-1)
Recommended Standards
- Reserpine Impurity 4 (CAS 1178-28-5)
- Budesonide EP Impurity E (CAS 131918-64-4)
- Beclometasone Dipropionate Monohydrate EP Impurity U (CAS 79578-39-5)
- Budesonide EP Impurity D (Mixture of Epimer) (CAS 85234-63-5)
- Pemafibrate Impurity 59 (CAS CATO-C4X-290359)
- Tulobuterol Impurity N3 (CAS 2425-28-7)
- Carbazochrome impurity 46 (CAS CATO-C4X-229146)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com