Ambroxol Impurity 16 CAS 77820-58-7
| CAS No. | 77820-58-7 |
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ambroxol Impurity 16.
Ambroxol Impurity 16 (CAS 77820-58-7), molecular formula C8H8ClNO2 and molecular weight 185.61 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H8ClNO2, Ambroxol Impurity 16 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 185.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Ambroxol Impurity 16 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClNO2 |
| Molecular Weight | 185.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ambroxol Standards
- Ambroxol Impurity 19 (CAS 359867-42-8)
- Ambroxol Impurity 60 (CAS 59278-65-8)
- Ambroxol Impurity 52 (CAS 946122-05-0)
- Ambroxol impurity 62 (CAS 397323-70-5)
- Ambroxol Impurity 12 (CAS 23363-88-4)
- Ambroxol Impurity 13 (CAS 27489-60-7)
- Ambroxol Impurity 35 (CAS CATO-C4X-108535)
- Ambroxol Impurity 36 (CAS CATO-C4X-108536)
Recommended Standards
- 8-Chloro-3,4-dihydro-4-methyl-2H-pyridazino[4,5-b][1,4]oxazine (CAS 66643-52-5)
- Chloromezanone Impurity 2 (CAS 5465-90-7)
- 8-Chloro-2,3-dihydrobenzo[b][1,4]dioxin-6-amine (CAS 769073-83-8)
- D-(+)-(2-Chlorophenyl)glycine (CAS 86169-24-6)
- 3-Amino-N-(4-chlorophenyl)benzene-1-sulfonamide (CAS 327092-56-8)
- n-(2-Chlorobenzyl)pyrimidin-2-amine (CAS 23676-58-6)
- 4-(O-tolyl)butan-1-ol (CAS 196409-31-1)
- 1-Methyl-2-oxopiperidine-3-carboxylic acid (CAS 37464-03-2)
- 8-Chloro-2-(pyridin-3-yl)quinoline-4-carbonyl chloride (CAS 1203040-93-0)
- 2-Amino-6-propylpyrimidin-4-ol (CAS 19810-58-3)
- Ethyl 5-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3-carboxylate (CAS 93618-46-3)
- 3'-Chloro-3,4'-dimethyl-[1,1'-biphenyl]-4-carbaldehyde (CAS 1994157-12-8)
- 3-((4-Chlorophenyl)amino)-1-(4-methoxyphenyl)propan-1-one (CAS 95886-08-1)
- Insulin degludec (CAS 844439-96-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com