1-Bromo-2,4-dimethoxy-5-nitrobenzene CAS 778599-56-7
| CAS No. | 778599-56-7 |
| Molecular Formula | C8H8BrNO4 |
| Molecular Weight | 262.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Bromo-2,4-dimethoxy-5-nitrobenzene.
CATO supplies 1-Bromo-2,4-dimethoxy-5-nitrobenzene (CAS 778599-56-7), a certified reference material (molecular formula C8H8BrNO4, MW 262.06 g/mol) for analytical method development and quality control.
The molecular framework of 1-Bromo-2,4-dimethoxy-5-nitrobenzene (C8H8BrNO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Bromo-2,4-dimethoxy-5-nitrobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8BrNO4 |
| Molecular Weight | 262.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-1-((2-methyloxiran-2-yl)methyl)-4-nitro-1H-imidazole, 97% (CAS 1001314-80-2)
- 2-(5-Bromo-3-nitropyridin-2-ylamino)ethanol (CAS 1033202-32-2)
- 2-((5-Bromo-3-nitropyridin-2-yl)oxy)ethan-1-amine (CAS 1249637-77-1)
- 4-Bromo-3-nitro-1-(tetrahydrofuran-3-yl)-1H-pyrazole (CAS 1340409-03-1)
- 1-Bromo-3,5-dimethoxy-2-nitrobenzene (CAS 1379358-18-5)
- Methyl 5-bromo-2-hydroxy-3-(hydroxyamino)benzoate (CAS 1427460-43-2)
- 6-Bromo-3-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylic acid (CAS 1429204-41-0)
- 5-Bromo-2,6-dimethoxypyridine-3-carboxylic acid (CAS 1826110-12-6)
Recommended Standards
- 1-Bromo-2,3-dimethoxy-5-nitrobenzene (CAS 7461-55-4)
- 1-Bromo-2,5-dimethoxy-3-nitrobenzene (CAS 55034-12-3)
- 1-(3,5-Dichloro-4-fluorophenyl)pyrrolidine-2,5-dione (CAS 66832-14-2)
- 1-Bromo-2,5-dimethoxy-4-nitrobenzene (CAS 98545-68-7)
- 5-Methyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazin-3-amine (CAS 1479085-43-2)
- (E)-Ethyl 2-(3-chlorobenzylidene)-7-methyl-3-oxo-5-phenyl-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 5830-95-5)
- n-(Cyclopropylmethyl)-2,5-difluoroaniline (CAS 1156163-12-0)
- N-Propionyl-(2S)-bornane-10,2-sultam (CAS 128947-19-3)
- 3-(4-Bromo-2-methoxyphenyl)cyclobutanone (CAS 1467061-75-1)
- 6-(4-nitrophenyl)morpholin-3-one (CAS 70547-99-8)
- N-((2S,3R,4R,5R)-3,4,5,6-Tetrahydroxy-1-oxohexan-2-yl)acetamide (CAS 282727-46-2)
- 2-(4-(2-Fluorophenyl)piperazin-1-yl)quinoxaline (CAS 339105-07-6)
- Methyl hexahydrocyclopenta[b]pyrrole-3a(1H)-carboxylate (CAS 1784081-60-2)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
Why CATO?
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