1-(3,5-Dichloro-4-fluorophenyl)pyrrolidine-2,5-dione CAS 66832-14-2
| CAS No. | 66832-14-2 |
| Molecular Formula | C10H6Cl2FNO2 |
| Molecular Weight | 262.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3,5-Dichloro-4-fluorophenyl)pyrrolidine-2,5-dione.
CATO supplies 1-(3,5-Dichloro-4-fluorophenyl)pyrrolidine-2,5-dione (CAS 66832-14-2), a certified reference material (molecular formula C10H6Cl2FNO2, MW 262.06 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 1-(3,5-Dichloro-4-fluorophenyl)pyrrolidine-2,5-dione is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 262.06 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(3,5-Dichloro-4-fluorophenyl)pyrrolidine-2,5-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6Cl2FNO2 |
| Molecular Weight | 262.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Dichloro Standards
- 3,5-Dichloro-2,6-difluoro-4-(methylsulfonyl)pyridine (CAS 13239-87-7)
- 2,6-Dichloro-4-((trifluoromethyl)thio)aniline (CAS 99479-65-9)
- N-(3,4-Dichloro-phenyl)-2-hydrazinocarbonyl-acetamide (CAS 1147218-91-4)
- 4,6-Dichloro-2-morpholinopyrimidine-5-carbaldehyde (CAS 1282537-80-7)
- 2,4-Dichloro-7-fluoro-6-nitroquinazoline (CAS 1007308-75-9)
- 2,3-Dichloro-6-fluoro-7-nitroquinoxaline (CAS 153392-16-6)
- 2,4-Dichloro-3,5-Dinitrobenzonitrile (CAS 1930-71-8)
- 6,7-Dichloro-2-(methylthio)pyrido[2,3-d]pyrimidin-4(3H)-one (CAS 2763156-14-3)
Recommended Standards
- (3-Bromo-4-methoxy-5-nitrophenyl)methanol (CAS 2386434-21-3)
- 1-Bromo-2,3-dimethoxy-5-nitrobenzene (CAS 7461-55-4)
- 5-Bromo-2,6-dimethoxypyridine-3-carboxylic acid (CAS 1826110-12-6)
- 1-Bromo-2,4-dimethoxy-5-nitrobenzene (CAS 778599-56-7)
- Tetrabutylammonium phosphate monobasic (CAS 5574-97-0)
- Spiro[5.5]undecan-2-one (CAS 1781-81-3)
- 4-(Diphenylamino)phenol (CAS 25069-86-7)
- 2-(2,4-Dioxo-1,2-dihydropyrido[3,2-d]pyrimidin-3(4H)-yl)propanoic acid (CAS 552298-13-2)
- 1-(3-(2-Fluorophenyl)-1H-1,2,4-triazol-5-yl)ethanamine (CAS 1367796-03-9)
- (Des-Glu?)-ACTH (1-24) (human, bovine, rat) (CAS 1815617-95-8)
- 4-(2-(4-Bromophenoxy)acetyl)piperazin-2-one (CAS 930928-60-2)
- 4-Methoxy-4-methyl-N-(3-methylbutan-2-yl)pentan-2-amine (CAS 1038304-07-2)
- 4-(1,1,1-Trifluoro-2-hydroxypropan-2-yl)phenol (CAS 179632-68-9)
- D-Phe22-Tirzepatide (CAS CATO-CPTD788912)
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