1-(3-Chloro-4-hydroxyphenyl)-5-methoxy-1H-pyrazole-3-carboxamide CAS 77935-72-9
| CAS No. | 77935-72-9 |
| Molecular Formula | C11H10ClN3O3 |
| Molecular Weight | 267.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 267.67 g/mol gives 1-(3-Chloro-4-hydroxyphenyl)-5-methoxy-1H-pyrazole-3-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(3-Chloro-4-hydroxyphenyl)-5-methoxy-1H-pyrazole-3-carboxamide (CAS 77935-72-9) is a high-purity analytical reference standard with the molecular formula C11H10ClN3O3 and a molecular weight of 267.67 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 1-(3-Chloro-4-hydroxyphenyl)-5-methoxy-1H-pyrazole-3-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 267.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10ClN3O3 |
| Molecular Weight | 267.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 5-(2-Chloro-5-nitrophenyl)-3-propyl-1,2,4-oxadiazole (CAS 1119505-95-1)
- 6-(4-Chloro-3-nitrophenyl)-5-methyl-4,5-dihydropyridazin-3(2h)-one (CAS 117397-88-3)
- Ethyl 5-chloro-7-methyl-2-oxo-2H-pyrano[3,2-c]pyridine-3-carboxylate (CAS 1254830-70-0)
- 5-Chloro-4-hydroxy-8-methoxyquinoline-3-carbohydrazide (CAS 1315344-84-3)
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Recommended Standards
- 1-(3-Chloro-2,5-dimethoxyphenyl)-1h-pyrrole-2,5-dione (CAS 438532-74-2)
- 1-(3-chloro-4-methoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 932976-16-4)
- 3-(4-Chloro-3-methylphenoxy)-1-methyl-4-nitro-1H-pyrazole (CAS 1443278-95-2)
- 2-((4-Chloro-6-(methylamino)pyrimidin-5-yl)methyl)furan-3-carboxylic acid (CAS 64261-20-7)
- Methyl N,N'-dicyclohexylcarbamimidate (CAS 6257-10-9)
- Dasatinib (CAS 302962-49-8)
- 2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-phenylacetamide (CAS 332161-36-1)
- 1-(2,4-Dimethylphenyl)pentane-1,3-dione (CAS 1040073-28-6)
- 2-(Benzylamino)-2-(3,4-dichlorophenyl)acetonitrile (CAS 674768-69-5)
- 6-Fluoro-4-nitro-1,2-dihydro-3H-indazol-3-one (CAS 885520-19-4)
- 2-Chloro-9-ethyl-9H-purin-6-amine (CAS 80395-87-5)
- 2-Isopropoxypropanehydrazide hydrochloride (CAS 1049750-51-7)
- 1-Nitro-3-propoxy-5-(trifluoromethyl)benzene (CAS 1881332-28-0)
- Insulin aspart (CAS 116094-23-6)
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