2-(trifluoromethyl)-1H-imidazole-5-carboxylic acid CAS 78016-98-5
| CAS No. | 78016-98-5 |
| Molecular Formula | C5H7F3N2O2 |
| Molecular Weight | 184.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 2-(trifluoromethyl)-1H-imidazole-5-carboxylic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-(trifluoromethyl)-1H-imidazole-5-carboxylic acid (CAS 78016-98-5), a certified reference material (molecular formula C5H7F3N2O2, MW 184.12 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(trifluoromethyl)-1H-imidazole-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H7F3N2O2 |
| Molecular Weight | 184.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related trifluoromethyl Standards
- 1-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 1402664-77-0)
- 4-(trifluoromethyl)-1H-imidazole-2-carboxylic acid (CAS 915230-46-5)
- 2-(Trifluoromethyl)tetrahydrofuran-3-carboxylic acid (CAS 1248551-27-0)
- 4-(Trifluoromethyl)tetrahydrofuran-3-carboxylic acid (CAS 1546333-88-3)
- 5-(trifluoromethyl)furan-3-carboxylic acid (CAS 56286-81-8)
- 5-(trifluoromethyl)oxolane-2-carboxylic acid (CAS 77899-95-7)
- rel-2-(Trifluoromethyl)tetrahydrofuran-3-carboxylic acid (CAS 2307772-40-1)
- 3-[(trifluoromethyl)sulfanyl]-1h-1,2,4-triazol-5-amine (CAS 1154963-41-3)
Recommended Standards
- 3-Fluorophthalic acid (CAS 1583-67-1)
- 2-Fluoro-4-nitrobenzamide (CAS 350-32-3)
- 5-Fluoroisophthalic Acid (CAS 1583-66-0)
- 3-Fluoro-4-nitrobenzamide (CAS 3556-52-3)
- 7-[1-(2,6-Dimethylphenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine (CAS 477865-17-1)
- 1-(4-Aminophenyl)-2-chloro-2-(methylsulfonyl)propan-1-one (CAS 1707402-68-3)
- 2-Chloro-1-[(4-methylbenzene)sulfonyl]-1H-pyrrole (CAS 1821332-27-7)
- Carboprost Methyl Ester (CAS 35700-21-1)
- Cycloserine Impurity N1 (CAS 15996-22-2)
- Benzyl ((1-(2-aminoethyl)piperidin-3-yl)methyl)carbamate (CAS 1353974-97-6)
- Trinonadecanoin (CAS 26536-13-0)
- 4-Chloro-6-(4-fluorophenyl)thieno[2,3-d]pyrimidine (CAS 1217309-73-3)
- 1216977-92-2 5-(3-Bromophenyl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1216977-92-2)
- Peptide-GMF (CAS CATO-CPTD788469)
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