4-(Trifluoromethyl)tetrahydrofuran-3-carboxylic acid CAS 1546333-88-3
| CAS No. | 1546333-88-3 |
| Molecular Formula | C6H7F3O3 |
| Molecular Weight | 184.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Trifluoromethyl)tetrahydrofuran-3-carboxylic acid (CAS 1546333-88-3) is a high-purity analytical reference standard with the molecular formula C6H7F3O3 and a molecular weight of 184.11 g/mol.
The molecular framework of 4-(Trifluoromethyl)tetrahydrofuran-3-carboxylic acid (C6H7F3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7F3O3 |
| Molecular Weight | 184.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 2-(Trifluoromethyl)tetrahydrofuran-3-carboxylic acid (CAS 1248551-27-0)
- 5-(trifluoromethyl)furan-3-carboxylic acid (CAS 56286-81-8)
- 5-(trifluoromethyl)oxolane-2-carboxylic acid (CAS 77899-95-7)
- rel-2-(Trifluoromethyl)tetrahydrofuran-3-carboxylic acid (CAS 2307772-40-1)
- 1-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 1402664-77-0)
- 2-(trifluoromethyl)-1H-imidazole-5-carboxylic acid (CAS 78016-98-5)
- 4-(trifluoromethyl)-1H-imidazole-2-carboxylic acid (CAS 915230-46-5)
- 3-[(trifluoromethyl)sulfanyl]-1h-1,2,4-triazol-5-amine (CAS 1154963-41-3)
Recommended Standards
- 2-Carboxy-4-nitropyridine 1-oxide (CAS 14933-78-9)
- 6-Hydroxy-5-nitropicolinic acid (CAS 1595036-59-1)
- 1-((Trifluoromethoxy)methyl)cyclopropane-1-carboxylic acid (CAS 1408279-84-4)
- cis-3-hydroxy-3-(trifluoromethyl)cyclobutanecarboxylic acid (CAS 1690177-86-6)
- 7-Bromo-3-methyl-2-(3-(trifluoromethyl)phenyl)quinoline-4-carboxylic acid (CAS 1336964-24-9)
- Phenyl-4-bromo-2-ethoxybenzamide (CAS 1261918-68-6)
- (E)-N-(4-(((1H-Pyrrol-2-yl)methylene)amino)phenyl)acetamide (CAS 646034-67-5)
- 2-(3-Chlorophenyl)thiazole-4-carbaldehyde (CAS 859850-99-0)
- Loratadine Impurity 31 (CAS 31255-47-7)
- 2-(5-bromo-1,3-thiazol-4-yl)acetonitrile (CAS 1909319-59-0)
- 6-Methylpyrazolo[1,5-a]pyrimidin-3-amine hydrochloride (CAS 1431964-56-5)
- 2-(3,4-Dichlorophenyl)-4,5-dimethyl-2,3-dihydro-1h-pyrazol-3-imine (CAS 1356744-23-4)
- 2-(Methylthio)-4-phenylpyrimidine (CAS 56734-10-2)
- Insulin Degludec Impurity 15 (CAS CATO-C4X-215715)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com