6,6'-Methylenebis(benzo[d][1,3]dioxol-5-ol) CAS 78188-48-4
| CAS No. | 78188-48-4 |
| Molecular Formula | C15H12O6 |
| Molecular Weight | 288.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6,6'-Methylenebis(benzo[d][1,3]dioxol-5-ol).
6,6'-Methylenebis(benzo[d][1,3]dioxol-5-ol) (CAS 78188-48-4) is a high-purity analytical reference standard with the molecular formula C15H12O6 and a molecular weight of 288.25 g/mol.
Structurally, 6,6'-Methylenebis(benzo[d][1,3]dioxol-5-ol) (C15H12O6) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 288.25 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12O6 |
| Molecular Weight | 288.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
Related Methylenebis Standards
- 3,3'-Methylenebis(2-hydroxybenzoic acid) (CAS 5578-67-6)
- 4,4'-Methylenebis(3-nitroaniline) (CAS 26946-33-8)
- Methylenebis[dimethyl(2-pyridyl)silane] (CAS 243468-48-6)
- 5,5'-Methylenebis(2-aminobenzoic acid) (CAS 7330-46-3)
- 5,5'-Methylenebis(3,4-dimethyl-1H-pyrrole-2-carboxylic acid) (CAS 27226-49-9)
- 1,1'-(Methylenebis(2-hydroxy-5,1-phenylene))diethanone (CAS 28467-22-3)
- 2,2'-((Methylenebis(oxy))bis(methylene))bis(2-(hydroxymethyl)propane-1,3-diol) (CAS 6228-26-8)
- 2,2-Methylenebis(5,5-dimethylcyclohexane-1,3-dione) (CAS 2181-22-8)
Recommended Standards
- 5,5-Dimethyl-1-hexanol (CAS 2768-18-5)
- Amflutizole (CAS 82114-19-0)
- 5,5-Bis(4-fluorophenyl)imidazolidine-2,4-dione (CAS 70028-85-2)
- BENZOYLOXYPHLORACETOPHENONE, OMEGA-(RG) (CAS 65982-77-6)
- (2S,3R,4S)-Hexane-1,2,3,4,6-pentaol (CAS 25029-33-8)
- 6-Carbamoyl-4-cyclopropoxynicotinic acid (CAS 1243458-51-6)
- 3-Amino-N-(5-chloro-2-methylphenyl)-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide (CAS 332949-93-6)
- 4-(4-Bromophenyl)-2,6-dichloropyrimidine (CAS 1490189-81-5)
- 4-(4,5-dichloro-1H-imidazol-1-yl)-2,6-bis(trifluoromethyl)pyridine (CAS 650592-45-3)
- 3-(5-Nitrofuran-2-yl)-1-(pyridin-2-yl)-1H-pyrazole-4-carbaldehyde (CAS 61651-01-2)
- 1-Tosylpiperazine (CAS 27106-51-0)
- 1-[4-(Aminomethyl)phenyl]-N-phenylmethanesulfonamide (CAS 1041556-68-6)
- (2E)-1-(3,4-Dichlorophenyl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one (CAS 1068507-62-9)
- (DTyr27,36,DThr32)-Neuropeptide Y (27-36) (CAS 163887-48-7)
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