Proparacaine Impurity 28 CAS 78329-81-4
| CAS No. | 78329-81-4 |
| Molecular Formula | C15H24N2O3 |
| Molecular Weight | 280.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Proparacaine Impurity 28 (C15H24N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Proparacaine Impurity 28 (CAS 78329-81-4) is a certified pharmaceutical impurity reference standard with the molecular formula C15H24N2O3 and a molecular weight of 280.36 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Proparacaine Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H24N2O3 |
| Molecular Weight | 280.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 2 |
Related Proparacaine Standards
- Proparacaine Impurity 13 (CAS CATO-C4X-202713)
- Proparacaine Impurity 16 (CAS 15788-85-9)
- Proparacaine Impurity 33 (CAS 754936-74-8)
- Proparacaine Impurity 15 (CAS 2102411-30-1)
- Proparacaine Impurity 24 (CAS 2815508-81-5)
- Proparacaine Impurity 29 (CAS CATO-C4X-202729)
- Proparacaine (CAS 499-67-2)
- Proparacaine Impurity 27 (CAS CATO-C4X-202727)
Recommended Standards
- Tetracaine Impurity 9 (CAS 55750-02-2)
- Pentachloroanisole (CAS 1825-21-4)
- Anhydro Dihydro Artemisinin (CAS 82596-30-3)
- N-(6,7-Dihydro-5H-[1,2,4]triazolo[3,4-b][1,3]thiazin-3-yl)-2-(thiophen-2-yl)acetamide (CAS 1030105-23-7)
- Cefmenoxime Impurity 2 (CAS 66340-45-2)
- Olmesartan Impurity 32 (CAS 1092980-85-2)
- Fasudil Impurity 13 (CAS 56344-32-2)
- Disperse Black 2 (CAS 6232-57-1)
- 2-Chloro-3,3-dimethyl-3H-indole (CAS 99058-18-1)
- 5-((1,5-Dimethyl-1H-pyrazol-4-yl)methylene)-2-thioxoimidazolidin-4-one (CAS 1005682-01-8)
- 2-(4-bromo-2-chlorophenyl)-2-methyloxirane (CAS 1557729-73-3)
- N-(4-Isopropylphenyl)cyclopropanesulfonamide (CAS 1207041-39-1)
- 3-Fluoro-6-iodo-2-nitroaniline (CAS 1955534-80-1)
- C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 127869-51-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com