4-Fluorobicyclo[2.2.2]octan-1-amine CAS 78385-91-8
| CAS No. | 78385-91-8 |
| Molecular Formula | C8H14FN |
| Molecular Weight | 143.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 143.20 g/mol gives 4-Fluorobicyclo[2.2.2]octan-1-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Fluorobicyclo[2.2.2]octan-1-amine (CAS 78385-91-8), molecular formula C8H14FN and molecular weight 143.20 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, fluorine substitution, 4-Fluorobicyclo[2.2.2]octan-1-amine is typically white to off-white liquid. Its solid-state physicochemical attributes — including a molecular weight of 143.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H14FN |
| Molecular Weight | 143.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorobicyclo Standards
- 8-Fluorobicyclo[3.2.1]Octan-3-amine (CAS 1934484-03-3)
- 3-Fluorobicyclo[3.2.1]Octan-8-amine (CAS 2168669-08-5)
- 5-Fluorobicyclo[2.2.2]Octan-2-amine (CAS 2168914-25-6)
- 2-{3-fluorobicyclo[1.1.1]pentan-1-yl}acetic acid (CAS 2092067-90-6)
- 4-Fluorobicyclo[2.1.1]Hexane-1-carboxylic acid (CAS 2091468-54-9)
- methyl 3-fluorobicyclo[1.1.1]pentane-1-carboxylate (CAS 262851-99-0)
- (4-Fluorobicyclo[2.2.1]heptan-1-yl)methanol (CAS 88888-24-8)
- 4-fluorobicyclo[2.2.2]octan-1-ol (CAS 22947-61-1)
Recommended Standards
- 1-Fluoro-7-azaspiro[3.5]Nonane (CAS 2092224-41-2)
- 6-(Fluoromethyl)bicyclo[4.1.0]Heptan-3-amine (CAS 2387597-29-5)
- (1R,5S)-3-fluoro-9-azabicyclo[3.3.1]Nonane (CAS 2165857-32-7)
- 7-Fluoro-2-azaspiro[3.5]Nonane (CAS 2091299-06-6)
- 1-(Tert-butyl)-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (CAS 874299-09-9)
- 2-((1-Oxo-1,2-dihydroisoquinolin-5-yl)oxy)propanoic acid (CAS 62000-97-9)
- 2-(2-(2-Hydroxyphenyl)-4,5-dihydrothiazol-4-yl)-3,4-dimethylthiazolidine-4-carboxylic acid (CAS 124508-94-7)
- 2-(But-3-en-1-yl)-5-methylcyclopentanone (CAS 38382-17-1)
- Tert-butyl (1R,5S)-3-(2-ethoxy-2-oxoethyl)-8-azabicyclo[3.2.1]Octane-8-carboxylate (CAS 273207-47-9)
- 6-Chloro-8-cyclopropyl-9H-purine (CAS 1044764-94-4)
- Methyl 3-hexyl-[2,2'-bithiophene]-5-carboxylate (CAS 918826-01-4)
- 3,4-Dichloro-5-methylbenzotrifluoride (CAS 1806283-89-5)
- Bumetanide Impurity 32 (CAS 22892-95-1)
- Insulin Degludec Impurity 7 (CAS CATO-C4X-21577)
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