5-Bromo-1-(2,6-difluorobenzyl)-1H-pyrazole CAS 784190-13-2

Purity 97%+In StockPharmaceutical Standards
CAS No.784190-13-2
Molecular FormulaC10H7BrF2N2
Molecular Weight273.08 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-1-(2,6-difluorobenzyl)-1H-pyrazole CAS 784190-13-2 chemical structure

Description

5-Bromo-1-(2,6-difluorobenzyl)-1H-pyrazole (CAS 784190-13-2), molecular formula C10H7BrF2N2 and molecular weight 273.08 g/mol, is a CATO reference standard with documented purity and traceability.

5-Bromo-1-(2,6-difluorobenzyl)-1H-pyrazole (C10H7BrF2N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Bromo-1-(2,6-difluorobenzyl)-1H-pyrazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H7BrF2N2
Molecular Weight273.08 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentF/Br-containing
Nitrogen Atoms2

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