(2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol CAS 78450-97-2
| CAS No. | 78450-97-2 |
| Molecular Formula | C5H3ClF3NOS |
| Molecular Weight | 217.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 78450-97-2) is a high-purity analytical reference standard with the molecular formula C5H3ClF3NOS and a molecular weight of 217.60 g/mol.
(2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol (C5H3ClF3NOS) contains an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2-Chloro-4-(trifluoromethyl)thiazol-5-yl)methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3ClF3NOS |
| Molecular Weight | 217.60 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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