Neomycin Impurity 12 CAS 78524-73-9

Description

Compared with other compounds in its class, the molecular weight of 615.63 g/mol gives Neomycin Impurity 12 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Neomycin Impurity 12 (CAS 78524-73-9), a pharmacopoeial impurity reference standard (molecular formula C23H45N5O14, MW 615.63 g/mol) used for the identification and quantification of trace impurities in APIs.

Neomycin Impurity 12 (C23H45N5O14) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Neomycin Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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