4-([1,1'-Biphenyl]-4-yl)cyclohexanone CAS 78531-65-4
| CAS No. | 78531-65-4 |
| Molecular Formula | C18H18O |
| Molecular Weight | 250.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-([1,1'-Biphenyl]-4-yl)cyclohexanone (CAS 78531-65-4) is a high-purity analytical reference standard with the molecular formula C18H18O and a molecular weight of 250.33 g/mol.
The molecular framework of 4-([1,1'-Biphenyl]-4-yl)cyclohexanone (C18H18O) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 4-([1,1'-Biphenyl]-4-yl)cyclohexanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H18O |
| Molecular Weight | 250.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
Related Biphenyl Standards
- Biphenyl, 4-(4-methylcyclohexyl)-,trans- (CAS 28864-96-2)
- 1-([1,1'-Biphenyl]-3-yl)-2,2,2-trifluoroethanone (CAS 1256466-96-2)
- 1-([1,1'-biphenyl]-2-yl)-2,2,2-trifluoroethan-1-one (CAS 302912-29-4)
- 1-([1,1'-biphenyl]-4-yl)-2,2,2-trifluoroethan-1-one (CAS 2369-31-5)
- [1,1`-Biphenyl]-2,2`,4,4`,5,5`-hexaol (CAS 76625-61-1)
- [1,1'-Biphenyl]-3,3',4,4',5,5'-hexol (CAS 4371-21-5)
- 1-([1,1'-biphenyl]-2-yl)-2,2,2-trifluoroethan-1-amine (CAS 843608-49-1)
- 1-([1,1'-biphenyl]-4-yl)-2,2,2-trifluoroethan-1-amine (CAS 886370-48-5)
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