3-((2-Fluorobenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazol-4-amine CAS 786660-58-0
| CAS No. | 786660-58-0 |
| Molecular Formula | C10H8F4N4S |
| Molecular Weight | 292.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-((2-Fluorobenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazol-4-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-((2-Fluorobenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazol-4-amine (CAS 786660-58-0), a certified reference material (molecular formula C10H8F4N4S, MW 292.26 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution, 3-((2-Fluorobenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazol-4-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 292.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-((2-Fluorobenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazol-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8F4N4S |
| Molecular Weight | 292.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Fluorobenzyl Standards
- N1-(4-Fluorobenzyl)-N2-((5-methyl-1,3,4-oxadiazol-2-yl)methyl)oxalamide (CAS 1209246-72-9)
- 3-(2-Fluorobenzyl)-2-thioxo-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one (CAS 440327-83-3)
- 3-(4-Fluorobenzyl)-2-thioxo-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one (CAS 440323-56-8)
- N-(4-fluorobenzyl)-2-iodoacetamide (CAS 99366-37-7)
- 6-(4-Fluorobenzyl)-2-thioxo-2,3,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-4(1H)-one (CAS 866873-03-2)
- 3-(4-Fluorobenzyl)-4-hydroxy-1-(3-methoxypropyl)pyridin-2(1H)-one (CAS 478247-81-3)
- 2-Fluorobenzyl (furan-2-carbonyl)alaninate (CAS 1008244-02-7)
- (S)-6-((4-Fluorobenzyl)oxy)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (CAS 187235-33-2)
Recommended Standards
- 2-Bromo-N-(2,4-dimethylpentan-3-yl)-3,3-dimethylbutanamide (CAS 69959-85-9)
- 3-(4-Methoxyphenyl)-7-(trifluoromethyl)-1H-indazole (CAS 680611-14-7)
- 2-{[(4-fluoro-3-nitrophenyl)amino]methyl}-6-methoxyphenol (CAS 306730-34-7)
- 4-(3,5-Dimethyl-1H-pyrazol-1-yl)-2-(trifluoromethyl)quinazoline (CAS 303148-66-5)
- 3-(1,3-Dioxan-2-yl)-4-nitropropiophenone (CAS 898786-24-8)
- 1-(2-PYRIMIDINYL)-1H-4-PYRIDINONE (CAS 29049-26-1)
- 2-(6,7-Dimethoxy-2-methyl-4-oxoquinazolin-3(4H)-yl)acetic acid (CAS 1322604-66-9)
- N-(6-chloropyridin-3-yl)-3,4-difluorobenzamide (CAS 325457-89-4)
- 3-(4-Nitrophenyl)-5-(thiophen-2-yl)-1,2,4-oxadiazole (CAS 54608-96-7)
- 4-[(2,5-Dioxotetrahydro-1H-imidazol-4-yliden)methyl]phenyl 3-Chloro-2,2-dimethylpropanoate (CAS 245072-83-7)
- (E)-N-hydroxy-2-nitrobenzimidoyl chloride (CAS 35447-75-7)
- 6-(3,5-Dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazin-3-amine (CAS 139047-73-7)
- Diethyl 4,5-dioxocyclopentane-1,3-dicarboxylate (CAS 10088-87-6)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com