2-{[(4-fluoro-3-nitrophenyl)amino]methyl}-6-methoxyphenol CAS 306730-34-7
| CAS No. | 306730-34-7 |
| Molecular Formula | C14H13FN2O4 |
| Molecular Weight | 292.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-{[(4-fluoro-3-nitrophenyl)amino]methyl}-6-methoxyphenol.
CATO supplies 2-{[(4-fluoro-3-nitrophenyl)amino]methyl}-6-methoxyphenol (CAS 306730-34-7), a certified reference material (molecular formula C14H13FN2O4, MW 292.26 g/mol) for analytical method development and quality control.
The molecular framework of 2-{[(4-fluoro-3-nitrophenyl)amino]methyl}-6-methoxyphenol (C14H13FN2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-{[(4-fluoro-3-nitrophenyl)amino]methyl}-6-methoxyphenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13FN2O4 |
| Molecular Weight | 292.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2,6-Diamino-5-(7,7,7-trifluoro-6-oxoheptyl)pyrimidin-4(1H)-one (CAS 647831-32-1)
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- 2-(8-ethyl-1-naphthyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2621934-04-9)
- 3-((2-Fluorobenzyl)thio)-5-(trifluoromethyl)-4H-1,2,4-triazol-4-amine (CAS 786660-58-0)
- 4-((((1-Ethyl-1H-pyrazol-3-yl)methyl)amino)methyl)benzoic acid (CAS 1006465-75-3)
- 2-Bromo-4-(difluoromethyl)-3-methoxy-6-methylpyridine (CAS 1805246-20-1)
- (R)-2-Chloro-alpha-methylbenzyl Alcohol (CAS 120466-66-2)
- N-(piperidin-2-ylmethyl)aminosulfonamide hydrochloride (CAS 1909309-20-1)
- Copper(II) undec-2-enoate (CAS 1328-71-8)
- Ixazomib Impurity 31 (CAS 50-73-7)
- 3-(1-Isobutyl-1H-pyrazol-3-yl)propiolic acid (CAS 1354704-47-4)
- 6-Chloro-N4-(2,2-dimethoxyethyl)pyrimidine-2,4-diamine (CAS 1158371-86-8)
- 4-(2-Aminoethyl)thiomorpholine (CAS 53515-36-9)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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