(R)-2-Amino-4-phosphonobutanoic acid CAS 78739-01-2

Purity 97%+In StockPharmaceutical Standards
CAS No.78739-01-2
Molecular FormulaC4H8NO5P
Molecular Weight181.08 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(R)-2-Amino-4-phosphonobutanoic acid CAS 78739-01-2 chemical structure

Description

The occurrence of (R)-2-Amino-4-phosphonobutanoic acid is closely related to a carbohydrate-derived structure, an amide group, a phosphate ester group in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(R)-2-Amino-4-phosphonobutanoic acid (CAS 78739-01-2) is a high-purity analytical reference standard with the molecular formula C4H8NO5P and a molecular weight of 181.08 g/mol.

The molecular framework of (R)-2-Amino-4-phosphonobutanoic acid (C4H8NO5P) is characterized by a carbohydrate-derived structure, an amide group, a phosphate ester group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (R)-2-Amino-4-phosphonobutanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC4H8NO5P
Molecular Weight181.08 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)1.5
CAS Registry Year (est.)1979
Nitrogen Atoms1

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