2,5-Bis(chloromethyl)thiophene CAS 28569-48-4
| CAS No. | 28569-48-4 |
| Molecular Formula | C6H6Cl2S |
| Molecular Weight | 181.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2,5-Bis(chloromethyl)thiophene (C6H6Cl2S) contains sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 181.08 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2,5-Bis(chloromethyl)thiophene (CAS 28569-48-4) is a high-purity analytical reference standard with the molecular formula C6H6Cl2S and a molecular weight of 181.08 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,5-Bis(chloromethyl)thiophene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6Cl2S |
| Molecular Weight | 181.08 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Bis Standards
- 3,4-Bis(chloromethyl)thiophene (CAS 18448-62-9)
- 1,4-Bis(chloromethyl)cyclohexane (CAS 824-93-1)
- 2-(Chloromethyl)-5-(methylsulfanyl)-1,3,4-thiadiazole (CAS 3914-48-5)
- 1-(chloromethyl)-4-cyclobutylbenzene (CAS 1379078-16-6)
- 5-(Chloromethyl)-1,2,3,4-tetrahydronaphthalene (CAS 17450-62-3)
- 6-(Chloromethyl)-1,2,3,4-tetrahydronaphthalene (CAS 17450-63-4)
- ((1-(Chloromethyl)cyclopropyl)methyl)benzene (CAS 180331-51-5)
- chloromethyl 2-ethoxy-2-methylpropanoate (CAS 1000296-74-1)
Recommended Standards
- (R)-2-Amino-4-phosphonobutanoic acid (CAS 78739-01-2)
- Bis(2,2,2-trifluoroethyl)amine (CAS 407-01-2)
- 3-Fluoro-5-(trifluoromethyl)pyridin-2-ol (CAS 1040683-15-5)
- (S)-1,1,1,4,4,4-Hexafluoro-2-butylamine (CAS 1349699-79-1)
- 2-Fluoro-3-nitrobenzoic acid methyl ester (CAS 946126-94-9)
- JH295 (CAS 1311143-71-1)
- 3-Amino-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 627053-26-3)
- Methyl 3-Boc-3-azabicyclo[3.2.1]octane-8-carboxylate (CAS 1403766-87-9)
- Ethyl 5-bromo-2-(4H-1,2,4-triazol-4-yl)benzoate (CAS 1351393-23-1)
- 4-Bromo-3-(difluoromethyl)-6-hydroxy-2-methylpyridine (CAS 1805347-39-0)
- 2-Bromo-6-fluoro-3-methoxyaniline (CAS 1534470-48-8)
- 2-Methoxythiazol-5-amine (CAS 1314355-65-1)
- 4-Amino-6-(difluoromethyl)-5-hydroxypicolinoyl chloride (CAS 1805337-15-8)
- Semaglutide impurity 96 (CAS CATO-C4X-222696)
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