4-Methoxy-2-methyl-3-nitropyridine CAS 78757-25-2
| CAS No. | 78757-25-2 |
| Molecular Formula | C7H8N2O3 |
| Molecular Weight | 168.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Methoxy-2-methyl-3-nitropyridine (CAS 78757-25-2), molecular formula C7H8N2O3 and molecular weight 168.15 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C7H8N2O3, 4-Methoxy-2-methyl-3-nitropyridine contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 168.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Methoxy-2-methyl-3-nitropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O3 |
| Molecular Weight | 168.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 2 |
Related Methoxy Standards
- 2-Methoxy-6-methyl-3-nitropyridine (CAS 112163-03-8)
- 5-Methoxy-2-methylpyrimidine-4-carboxylic acid (CAS 113949-10-3)
- 6-Methoxy-5-methylpyrimidine-4-carboxylic acid (CAS 1211507-53-7)
- 5-Methoxy-2-methyl-3-nitropyridine (CAS 1211534-67-6)
- 2-Methoxy-4-methylpyrimidine-5-carboxylic acid (CAS 1228113-00-5)
- 5-Methoxy-3-methylpyrazine-2-carboxylic Acid (CAS 1262860-60-5)
- (6S)-6-Methoxy-4,6-dihydrofuro[3,2-c]pyran-2-one (CAS 131149-16-1)
- 2-Methoxy-6-methylpyrimidine-4-carboxylic acid (CAS 136518-00-8)
Recommended Standards
- 4-Hydroxy-2-methoxybenzoic acid (CAS 90111-34-5)
- 4-Methoxy-2-methyl-5-nitropyridine (CAS 789474-20-0)
- 4-Hydrazinyl-2-methylpyrimidine-5-carboxylic acid (CAS 98135-49-0)
- 4-methoxy-2-methylpyrimidine-5-carboxylic acid (CAS 72411-88-2)
- 1-(4-Bromophenyl)cyclohexanol (CAS 19920-80-0)
- 8-Methyl-2,3,9,9a-tetrahydro-1H-pyrido[3,4-b]indol-1-one (CAS 14490-04-1)
- 3-(1-Piperidinyl)-D-Ala-OMe.HCl (CAS 2044710-72-5)
- 7-Chloro-2-(3-fluorophenyl)-2H-pyrazolo[3,4-d]pyridazine (CAS 1956379-51-3)
- (2-Chloro-5-fluoropyridin-4-yl)boronic acid (CAS 951677-47-7)
- rel-(2S,3S)-2-Methyl-piperidine-3-carboxylic acid (CAS 110287-65-5)
- 1-(Methylthio)-3-phenylpropan-2-one (CAS 86568-66-3)
- 2-(Methylthio)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine (CAS 2529569-27-3)
- 3-Bromo-2-(3,3-difluoroazetidin-1-yl)nitrobenzene (CAS 1707358-03-9)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
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