Diazoxide Impurity 15 CAS 78767-43-8
| CAS No. | 78767-43-8 |
| Molecular Formula | C6H6ClNO3S |
| Molecular Weight | 207.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 207.63 g/mol gives Diazoxide Impurity 15 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Diazoxide Impurity 15 (CAS 78767-43-8) is a certified pharmaceutical impurity reference standard with the molecular formula C6H6ClNO3S and a molecular weight of 207.63 g/mol.
Diazoxide Impurity 15 (C6H6ClNO3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO3S |
| Molecular Weight | 207.63 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Diazoxide Standards
- Diazoxide Impurity 16 (CAS 576997)
- Diazoxide Impurity 18 (CAS CATO-C4X-195218)
- Diazoxide Impurity 17 (CAS 89639-39-4)
- Diazoxide impurity 8 (CAS CATO-C4X-19528)
- Diazoxide Impurity 19 (CAS CATO-C4X-195219)
- Diazoxide impurity 9 (CAS CATO-C4X-19529)
- Diazoxide (CAS 364-98-7)
- Diazoxide Impurity 1 (CAS 5800-59-9)
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